Compile Data Set for Download or QSAR
Report error Found 294 of ki data for polymerid = 7531,9757,50001157
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022815BDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataKi:  20nMAssay Description:TP_TRANSPORTER: inhibition of Verapamil stimulated ATP hydrolysis in membranes from MDR1-expressing Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201796BDBM50201796(CHEBI:5677 | Hernandezine)
Affinity DataKi:  20nMAssay Description:Binding affinity to Vanadate-sensitive ABCB1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206310BDBM50206310(ELACRIDAR HYDROCHLORIDE | N-4-[2-(1,2,3,4-Tetrahyd...)
Affinity DataKi:  40nMAssay Description:TP_TRANSPORTER: transepithelial transport of digoxin (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012278BDBM50012278(VINBLASTINE SULFATE | (2ALPHA,2''BETA,3BETA,4ALPHA...)
Affinity DataKi:  100nMAssay Description:High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121978BDBM50121978(2-(6-Amino-3-imino-3H-xanthen-9-yl)-benzoic acid m...)
Affinity DataKi:  100nMAssay Description:High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017712BDBM50017712(Apoplon | 3,4,5-trimethoxybenzoyl methyl reserpate...)
Affinity DataKi:  100nMAssay Description:Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20607BDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataKi:  100nMAssay Description:Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115974BDBM50115974(CHEMBL3612170)
Affinity DataKi:  120nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115973BDBM50115973(CHEMBL3612151)
Affinity DataKi:  120nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153727BDBM50153727(CHEMBL3774695)
Affinity DataKi:  130nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50390978BDBM50390978(VALSPODAR)
Affinity DataKi:  134nMAssay Description:TP_TRANSPORTER: inhibition of ATPase activity (Verapamil) in P-gp-MRP-16-Protein A complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153737BDBM50153737(CHEMBL3774786)
Affinity DataKi:  190nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  200nMAssay Description:High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420182BDBM50420182(CHEMBL2074650)
Affinity DataKi:  210nMAssay Description:TP_TRANSPORTER: inhibition of Hydroxydoxorubicin efflux in K562/Adr cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115978BDBM50115978(CHEMBL3612172)
Affinity DataKi:  220nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115977BDBM50115977(CHEMBL3612153)
Affinity DataKi:  220nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153735BDBM50153735(CHEMBL3774970)
Affinity DataKi:  230nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153725BDBM50153725(CHEMBL3775153)
Affinity DataKi:  240nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153733BDBM50153733(CHEMBL3775128)
Affinity DataKi:  250nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153736BDBM50153736(CHEMBL3775201)
Affinity DataKi:  260nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153718BDBM50153718(CHEMBL450532)
Affinity DataKi:  280nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50486029BDBM50486029(CHEMBL2172398)
Affinity DataKi:  280nMAssay Description:Competitive inhibition of P-gp overexpressed in human MDA435/LCC6MDR cells assessed as accumulation of doxorubicin by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153719BDBM50153719(CHEMBL499498)
Affinity DataKi:  290nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088574BDBM50088574(CHEMBL3577218)
Affinity DataKi:  290nMAssay Description:Inhibition of human MDR1 transfected in mouse NIH/3T3 MDR1-G185 cells assessed as reduction in daunomycin accumulation after 30 mins by flow cytometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005628BDBM50005628(verapamil-S | 2-(3,4-Dimethoxy-phenyl)-5-{[2-(3,4-...)
Affinity DataKi:  300nMAssay Description:High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50154916BDBM50154916(CHEMBL3775786)
Affinity DataKi:  310nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153721BDBM50153721(CHEMBL3775788)
Affinity DataKi:  310nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115972BDBM50115972(CHEMBL3612169)
Affinity DataKi:  320nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115971BDBM50115971(CHEMBL3612150)
Affinity DataKi:  320nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153723BDBM50153723(CHEMBL3775488)
Affinity DataKi:  320nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50486029BDBM50486029(CHEMBL2172398)
Affinity DataKi:  340nMAssay Description:Competitive inhibition of P-gp overexpressed in human MDA435/LCC6MDR cells assessed as accumulation of doxorubicin by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353597BDBM50353597(CHEMBL1829396)
Affinity DataKi:  340nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH-3T3 cells assessed as daunomycin efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022815BDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataKi:  350nMAssay Description:TP_TRANSPORTER: transepithelial transport of digoxin (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353602BDBM50353602(CHEMBL1829522)
Affinity DataKi:  380nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH-3T3 cells assessed as daunomycin efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353600BDBM50353600(CHEMBL1829520)
Affinity DataKi:  390nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH-3T3 cells assessed as daunomycin efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485592BDBM50485592(CHEMBL350445)
Affinity DataKi:  400nMAssay Description:TP_TRANSPORTER: inhibition of Taxol transepithelial transport (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50154912BDBM50154912(CHEMBL3774875)
Affinity DataKi:  400nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153724BDBM50153724(CHEMBL3774484)
Affinity DataKi:  410nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153734BDBM50153734(CHEMBL3775696)
Affinity DataKi:  420nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275947BDBM50275947((5S,14R,19S,28R)-10,23-dimethoxy-4,4,29,29-tetrame...)
Affinity DataKi:  420nMAssay Description:Inhibition of human MDR1 overexpressed in mouse NIH/3T3 cells assessed as daunorubicin accumulation by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088576BDBM50088576(CHEMBL3577215)
Affinity DataKi:  420nMAssay Description:Inhibition of human MDR1 transfected in mouse NIH/3T3 MDR1-G185 cells assessed as reduction in daunomycin accumulation after 30 mins by flow cytometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121975BDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataKi:  430nMAssay Description:TP_TRANSPORTER: transepithelial transport of digoxin (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206310BDBM50206310(ELACRIDAR HYDROCHLORIDE | N-4-[2-(1,2,3,4-Tetrahyd...)
Affinity DataKi:  440nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) in MDR1-expressing MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153738BDBM50153738(CHEMBL3775556)
Affinity DataKi:  460nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353599BDBM50353599(CHEMBL1829518)
Affinity DataKi:  470nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH-3T3 cells assessed as daunomycin efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50154913BDBM50154913(CHEMBL3775570)
Affinity DataKi:  470nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115976BDBM50115976(CHEMBL3612171)
Affinity DataKi:  470nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115975BDBM50115975(CHEMBL3612152)
Affinity DataKi:  470nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116014BDBM50116014(CHEMBL3612160)
Affinity DataKi:  480nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116013BDBM50116013(CHEMBL3612141)
Affinity DataKi:  480nMAssay Description:Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
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