Compile Data Set for Download or QSAR
Report error Found 88 Enz. Inhib. hit(s) with all data for entry = 10179
TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518593(US11124523, Example (+)-28b)
Affinity DataEC50:  0.0400nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518565(US11124523, Example (+)-4)
Affinity DataEC50:  0.0700nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518566(US11124523, Example (+)-5)
Affinity DataEC50:  0.100nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataEC50:  0.100nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518577(US11124523, Example (+)-15)
Affinity DataEC50:  0.200nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518588(US11124523, Example (+)-24)
Affinity DataEC50:  0.200nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518590(US11124523, Example (+)-26)
Affinity DataEC50:  0.200nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518563(US11124523, Example (+)-2)
Affinity DataEC50:  0.470nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518578(US11124523, Example (+)-16)
Affinity DataEC50:  0.5nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518591(US11124523, Example (+)-27)
Affinity DataEC50:  0.800nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518557(US11124523, Comparative Compound 2)
Affinity DataEC50:  0.900nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518587(US11124523, Example (+)-23)
Affinity DataEC50:  1nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518573(US11124523, Example (+)-11)
Affinity DataEC50:  1.40nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518567(US11124523, Example (+)-6)
Affinity DataEC50:  1.80nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518570(US11124523, Example (+)-8)
Affinity DataEC50:  1.80nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518585(US11124523, Example (+)-21)
Affinity DataEC50:  2.20nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataEC50:  3nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518564(US11124523, Example (+)-3)
Affinity DataEC50:  3nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518582(US11124523, Example (+)-20)
Affinity DataEC50:  3.10nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518589(US11124523, Example (+)-25)
Affinity DataEC50:  4nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518575(US11124523, Example (+)-13)
Affinity DataEC50:  4.10nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518580(US11124523, Example (+)-18)
Affinity DataEC50:  4.20nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518581(US11124523, Example (+)-19)
Affinity DataEC50:  4.5nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518592(US11124523, Example (+)-28a)
Affinity DataEC50:  4.60nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518571(US11124523, Example (+)-9)
Affinity DataEC50:  6.10nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518574(US11124523, Example (+)-12)
Affinity DataEC50:  6.80nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518579(US11124523, Example (+)-17)
Affinity DataEC50:  8.90nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518560(US11124523, Example (+)-1b)
Affinity DataEC50:  10nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518572(US11124523, Example (+)-10)
Affinity DataEC50:  11.6nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518569(US11124523, Example (+)-7)
Affinity DataEC50:  14.1nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518576(US11124523, Example (+)-14)
Affinity DataEC50:  19.9nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518561(US11124523, Example (-)-1b)
Affinity DataEC50:  380nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518559(US11124523, Example (+)-1a)
Affinity DataEC50:  1.93E+3nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518562(US11124523, Example (-)-1a)
Affinity DataEC50:  2.34E+3nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataIC50: 4.60E+3nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM518593(US11124523, Example (+)-28b)
Affinity DataIC50: 5.30E+3nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataIC50: 5.50E+3nMAssay Description:To test the blocking effects of the compounds of the present disclosure on hERG potassium currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM518578(US11124523, Example (+)-16)
Affinity DataIC50: 1.27E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataIC50: 1.36E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM518570(US11124523, Example (+)-8)
Affinity DataIC50: 1.73E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM518587(US11124523, Example (+)-23)
Affinity DataIC50: 1.78E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataIC50: 1.88E+4nMAssay Description:To test the blocking effects of the compounds of the present disclosure on hERG potassium currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataIC50: 1.93E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM518571(US11124523, Example (+)-9)
Affinity DataIC50: 2.19E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandPNGBDBM518578(US11124523, Example (+)-16)
Affinity DataIC50: 2.28E+4nMAssay Description:To test the blocking effects of the compounds of the present disclosure on hERG potassium currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM518571(US11124523, Example (+)-9)
Affinity DataIC50: 2.34E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM518580(US11124523, Example (+)-18)
Affinity DataIC50: 2.45E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
TBA

US Patent
LigandPNGBDBM518578(US11124523, Example (+)-16)
Affinity DataIC50: 3.37E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM518560(US11124523, Example (+)-1b)
Affinity DataIC50: 3.55E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandPNGBDBM518563(US11124523, Example (+)-2)
Affinity DataIC50: 4.00E+4nMAssay Description:To test the blocking effects of the compounds of the present disclosure on hERG potassium currents.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

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