Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 11271
TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604240BDBM604240((2R,4S) N ((S)-1-((4-((Z) N′-((L-valyl)oxy)c...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604244BDBM604244(US11661418, Compound I-15)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604243BDBM604243(3-((2R,4S)-2-(((S)-1-((4-carbamimidoylbenzyl)amino...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604242BDBM604242(ethyl 3-((2R,4S)-2-(((S)-1-((4-carbamimidoylbenzyl...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604241BDBM604241((2R,4S)-2-(((S)-1-((4-carbamimidoylbenzyl)amino)-1...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604246BDBM604246((S) N-(4-carbamimidoylbenzyl)-1-((2R,4S)-1-methyl-...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604245BDBM604245(US11661418, Compound I-16)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604251BDBM604251((2R,4S) N ((S)-1-(((5-((Z) N-hydroxycarbamimidoyl)...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604250BDBM604250((2R,4S)-4-(3-(1H-pyrazol-1-yl)phenyl)-N ((S)-1-((5...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604249BDBM604249((2R,4S) N ((S)-1-((4-carbamimidoylbenzyl)amino)-1-...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604247BDBM604247(benzyl (imino(4-(((S)-1-((2R,4S)-4-phenylpiperidin...)
Affinity DataKi:  1.50E+3nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604252BDBM604252(US11661418, Compound I-31)
Affinity DataKi:  1.50E+3nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 604248BDBM604248(benzyl ((4-(((S)-2-((2R,4S)-1-ethyl-4-phenylpiperi...)
Affinity DataKi:  6.25E+3nMAssay Description:The MASP-2 assay protocol is carried out as follows. Test compounds are serially diluted in DMSO and then 100 nL of each dilution is transferred to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent