Compile Data Set for Download or QSAR
Report error Found 85 Enz. Inhib. hit(s) with all data for entry = 13588
TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792924BDBM792924(US12552795, Compound 1 | US20260138986, Compound 1)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472795BDBM472795(US10829493, Example 21 | US12552795, Compound 21 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472796BDBM472796(US10829493, Example 22 | US12552795, Compound 22 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472796BDBM472796(US10829493, Example 22 | US12552795, Compound 22 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 469288BDBM469288(US10807985, Compound 63 | US10829493, Example 63 o...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 469288BDBM469288(US10807985, Compound 63 | US10829493, Example 63 o...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472791BDBM472791(US10829493, Example 17 | US12552795, Compound 17 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472792BDBM472792(US10829493, Example 18 | US12552795, Compound 18 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472792BDBM472792(US10829493, Example 18 | US12552795, Compound 18 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472793BDBM472793(US10829493, Example 19 | US12552795, Compound 19 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472793BDBM472793(US10829493, Example 19 | US12552795, Compound 19 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472794BDBM472794(US10829493, Example 20 | US12552795, Compound 20 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472794BDBM472794(US10829493, Example 20 | US12552795, Compound 20 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472787BDBM472787(US10829493, Example 13 | US12552795, Compound 13 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472788BDBM472788(US10829493, Example 14 | US12552795, Compound 14 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472788BDBM472788(US10829493, Example 14 | US12552795, Compound 14 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472789BDBM472789(US10829493, Example 15 | US12552795, Compound 15 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472789BDBM472789(US10829493, Example 15 | US12552795, Compound 15 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472790BDBM472790(US10829493, Example 16 | US12552795, Compound 16 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472790BDBM472790(US10829493, Example 16 | US12552795, Compound 16 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472783BDBM472783(US10829493, Example 9 | US12552795, Compound 9 | U...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472784BDBM472784(US10829493, Example 10 | US12552795, Compound 11 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472784BDBM472784(US10829493, Example 10 | US12552795, Compound 11 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472784BDBM472784(US10829493, Example 10 | US12552795, Compound 11 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472786BDBM472786(US10829493, Example 12 | US12552795, Compound 12 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472786BDBM472786(US10829493, Example 12 | US12552795, Compound 12 |...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792928BDBM792928(US12552795, Compound 5 | US20260138986, Compound 5)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792929BDBM792929(US12552795, Compound 6 | US20260138986, Compound 6)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792929BDBM792929(US12552795, Compound 6 | US20260138986, Compound 6)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792930BDBM792930(US12552795, Compound 7 | US20260138986, Compound 7)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792930BDBM792930(US12552795, Compound 7 | US20260138986, Compound 7)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472782BDBM472782(US10829493, Example 8 | US12552795, Compound 8 | U...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472782BDBM472782(US10829493, Example 8 | US12552795, Compound 8 | U...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472783BDBM472783(US10829493, Example 9 | US12552795, Compound 9 | U...)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792924BDBM792924(US12552795, Compound 1 | US20260138986, Compound 1)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792925BDBM792925(US12552795, Compound 2 | US20260138986, Compound 2)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3 | US20260138986, Compound 3)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3 | US20260138986, Compound 3)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792927BDBM792927(US12552795, Compound 4 | US20260138986, Compound 4)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha [D842V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792927BDBM792927(US12552795, Compound 4 | US20260138986, Compound 4)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792928BDBM792928(US12552795, Compound 5 | US20260138986, Compound 5)
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472791BDBM472791(US10829493, Example 17 | US12552795, Compound 17 |...)
Affinity DataIC50: 0.650nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472784BDBM472784(US10829493, Example 10 | US12552795, Compound 11 |...)
Affinity DataIC50: 0.650nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792925BDBM792925(US12552795, Compound 2 | US20260138986, Compound 2)
Affinity DataIC50: 0.650nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472795BDBM472795(US10829493, Example 21 | US12552795, Compound 21 |...)
Affinity DataIC50: 0.650nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472787BDBM472787(US10829493, Example 13 | US12552795, Compound 13 |...)
Affinity DataIC50: 0.650nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792924BDBM792924(US12552795, Compound 1 | US20260138986, Compound 1)
Affinity DataKd: <10nMAssay Description:Kd Determinations. For most assays, including wt KIT kinase, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792925BDBM792925(US12552795, Compound 2 | US20260138986, Compound 2)
Affinity DataKd: <10nMAssay Description:Kd Determinations. For most assays, including wt KIT kinase, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 792926BDBM792926(US12552795, Compound 3 | US20260138986, Compound 3)
Affinity DataKd: <10nMAssay Description:Kd Determinations. For most assays, including wt KIT kinase, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 472794BDBM472794(US10829493, Example 20 | US12552795, Compound 20 |...)
Affinity DataKd: <10nMAssay Description:Kd Determinations. For most assays, including wt KIT kinase, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

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