Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 6350
LigandChemical structure of BindingDB Monomer ID 50403098BDBM50403098(CHEMBL2216893 | US8754089, 4-amino-6-(((1S)-1-(6-m...)
Affinity DataKi:  5nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124086BDBM124086(US8754089, 4-amino-6-(((1S)-1-(4-oxo-3-phenyl-4H-p...)
Affinity DataKi:  8.20nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124095BDBM124095(US8754089, 4-amino-6-((1-(6-methyl-4-oxo-3-(2-pyri...)
Affinity DataKi:  10.8nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124096BDBM124096(US8754089, 4-amino-6-((1-(6-methyl-4-oxo-3-phenyl-...)
Affinity DataKi:  12.6nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124083BDBM124083(US8754089, 4-amino-6-(((1S)-1-(3-(3-fluorophenyl)-...)
Affinity DataKi:  15.7nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124094BDBM124094(US8754089, 4-amino-6-((1-(4-oxo-3-phenyl-4H-pyrido...)
Affinity DataKi:  15.9nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124087BDBM124087(US8754089, 4-amino-6-(((1S)-1-(6-methyl-4-oxo-3-(2...)
Affinity DataKi:  21.4nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124077BDBM124077(US8754089, 3-(3-fluorophenyl)-6-methyl-2-((1S)-1-(...)
Affinity DataKi:  23.1nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124079BDBM124079(US8754089, 3-(3-fluorophenyl)-6-methyl-2-(1-(9H-pu...)
Affinity DataKi:  27.7nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124090BDBM124090(US8754089, 4-amino-6-((1-(3-(3,5-difluorophenyl)-6...)
Affinity DataKi:  33nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124085BDBM124085(US8754089, 4-amino-6-(((1S)-1-(4-oxo-3-(2-pyridiny...)
Affinity DataKi:  42.4nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124088BDBM124088(US8754089, 4-amino-6-((1-(3-(2-(methylsulfonyl)phe...)
Affinity DataKi:  52.8nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124091BDBM124091(US8754089, 4-amino-6-((1-(3-(3-fluorophenyl)-4-oxo...)
Affinity DataKi:  57.1nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124082BDBM124082(US8754089, 4-amino-6-(((1S)-1-(3-(3,5-difluorophen...)
Affinity DataKi:  63.7nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124097BDBM124097(US8754089, 6-methyl-2-(1-(9H-purin-6-ylamino)ethyl...)
Affinity DataKi:  80.2nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124074BDBM124074(US8754089, 2-((4-amino-3-iodo-1H-pyrazolo[3,4-d]py...)
Affinity DataKi:  84.9nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124089BDBM124089(US8754089, 4-amino-6-((1-(3-(3,5-difluorophenyl)-4...)
Affinity DataKi:  89nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124093BDBM124093(US8754089, 4-amino-6-((1-(4-oxo-3-(2-pyridinyl)-4H...)
Affinity DataKi:  104nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124103BDBM124103(US8754089, 7-fluoro-3-(3-fluorophenyl)-2-((1S)-1-(...)
Affinity DataKi:  110nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124100BDBM124100(US8754089, 7-fluoro-2-((1S)-1-(9H-purin-6-ylamino)...)
Affinity DataKi:  184nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124084BDBM124084(US8754089, 4-amino-6-(((1S)-1-(3-(4-methyl-2-pyrid...)
Affinity DataKi:  230nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124104BDBM124104(US8754089, 7-fluoro-3-(3-fluorophenyl)-2-(1-(9H-pu...)
Affinity DataKi:  360nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124092BDBM124092(US8754089, 4-amino-6-((1-(3-(4-methyl-2-pyridinyl)...)
Affinity DataKi:  471nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124101BDBM124101(US8754089, 7-fluoro-2-(1-(9H-purin-6-ylamino)ethyl...)
Affinity DataKi:  659nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124078BDBM124078(US8754089, 3-(3-fluorophenyl)-6-methyl-2-((9H-puri...)
Affinity DataKi:  711nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124076BDBM124076(US8754089, 3-(3-fluorophenyl)-6-methyl-2-((1R)-1-(...)
Affinity DataKi:  802nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124075BDBM124075(US8754089, 2-((6-amino-9H-purin-9-yl)methyl)-6-met...)
Affinity DataKi:  6.28E+3nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124081BDBM124081(US8754089, 4-amino-6-(((1R)-1-(4-oxo-3-phenyl-4H-p...)
Affinity DataKi:  6.32E+3nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124098BDBM124098(US8754089, 6-methyl-3-(2-methylphenyl)-2-((9H-puri...)
Affinity DataKi:  9.71E+3nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124102BDBM124102(US8754089, 7-fluoro-3-(3-fluorophenyl)-2-((1R)-1-(...)
Affinity DataKi:  1.98E+4nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124099BDBM124099(US8754089, 7-fluoro-2-((1R)-1-(9H-purin-6-ylamino)...)
Affinity DataKi:  2.15E+4nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 124080BDBM124080(US8754089, 4-amino-6-(((1R)-1-(3-(2-(methylsulfony...)
Affinity DataKi:  2.46E+4nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent