Compile Data Set for Download or QSAR
maximum 50k data
Found 52 Enz. Inhib. hit(s) with all data for entry = 50008628
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075421(7-(Ethyl-methanesulfonyl-amino)-1-(2-methoxy-benzy...)
Affinity DataIC50:  3.60nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075429(7-(Methanesulfonyl-methyl-amino)-1-(2-methoxy-benz...)
Affinity DataIC50:  8.60nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075422(7-(Methanesulfonyl-propyl-amino)-1-(2-methoxy-benz...)
Affinity DataIC50:  13nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075412(1-(2,5-Dimethoxy-benzyl)-4-(4-methoxy-phenyl)-2-ox...)
Affinity DataIC50:  21nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075435(7-Amino-1-(2-methoxy-benzyl)-4-(4-methoxy-phenyl)-...)
Affinity DataIC50:  27nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075412(1-(2,5-Dimethoxy-benzyl)-4-(4-methoxy-phenyl)-2-ox...)
Affinity DataIC50:  41nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075417(1-(2-Methoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50:  120nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075424(7-Methanesulfonylamino-1-(2-methoxy-benzyl)-4-(4-m...)
Affinity DataIC50:  120nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075428(1-(2-Methoxy-benzyl)-2-oxo-4-(3,4,5-trimethoxy-phe...)
Affinity DataIC50:  170nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075419(1-(2-Methoxy-benzyl)-4-(4-methoxy-phenyl)-7-nitro-...)
Affinity DataIC50:  200nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075413(4-(4-Methoxy-phenyl)-1-(2-methyl-benzyl)-2-oxo-1,2...)
Affinity DataIC50:  300nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075417(1-(2-Methoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50:  380nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075413(4-(4-Methoxy-phenyl)-1-(2-methyl-benzyl)-2-oxo-1,2...)
Affinity DataIC50:  420nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075415(4-(2,4-Dimethoxy-phenyl)-1-(2-methoxy-benzyl)-2-ox...)
Affinity DataIC50:  430nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075420(4-(2,5-Dimethoxy-phenyl)-1-(2-methoxy-benzyl)-2-ox...)
Affinity DataIC50:  490nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075416(1-(2-Isopropyl-benzyl)-4-(4-methoxy-phenyl)-2-oxo-...)
Affinity DataIC50:  660nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075416(1-(2-Isopropyl-benzyl)-4-(4-methoxy-phenyl)-2-oxo-...)
Affinity DataIC50:  710nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075418(1-(2-Ethoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,2...)
Affinity DataIC50:  900nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075426(4-Benzo[1,3]dioxol-5-yl-1-(2-methoxy-benzyl)-2-oxo...)
Affinity DataIC50:  1.20E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075415(4-(2,4-Dimethoxy-phenyl)-1-(2-methoxy-benzyl)-2-ox...)
Affinity DataIC50:  1.20E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075418(1-(2-Ethoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,2...)
Affinity DataIC50:  1.30E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075411(1-(2-Chloro-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,2...)
Affinity DataIC50:  1.30E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075433(1-(2-Methoxy-benzyl)-4-(3-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50:  1.50E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075434(1-(3-Methoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50:  1.60E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075426(4-Benzo[1,3]dioxol-5-yl-1-(2-methoxy-benzyl)-2-oxo...)
Affinity DataIC50:  1.90E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075419(1-(2-Methoxy-benzyl)-4-(4-methoxy-phenyl)-7-nitro-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075435(7-Amino-1-(2-methoxy-benzyl)-4-(4-methoxy-phenyl)-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075427(1-Benzyl-4-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-be...)
Affinity DataIC50:  2.70E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075411(1-(2-Chloro-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,2...)
Affinity DataIC50:  2.70E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075434(1-(3-Methoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50:  2.70E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075430(4-(4-Methoxy-phenyl)-1-(2-methylsulfanyl-benzyl)-2...)
Affinity DataIC50:  2.70E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075427(1-Benzyl-4-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-be...)
Affinity DataIC50:  3.00E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075433(1-(2-Methoxy-benzyl)-4-(3-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50:  3.50E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075425(1-(2,3-Dimethoxy-benzyl)-4-(4-methoxy-phenyl)-2-ox...)
Affinity DataIC50:  3.50E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075425(1-(2,3-Dimethoxy-benzyl)-4-(4-methoxy-phenyl)-2-ox...)
Affinity DataIC50:  5.20E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075430(4-(4-Methoxy-phenyl)-1-(2-methylsulfanyl-benzyl)-2...)
Affinity DataIC50:  6.40E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075420(4-(2,5-Dimethoxy-phenyl)-1-(2-methoxy-benzyl)-2-ox...)
Affinity DataIC50:  6.80E+3nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075436(1-(2,6-Dimethoxy-benzyl)-4-(4-methoxy-phenyl)-2-ox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075436(1-(2,6-Dimethoxy-benzyl)-4-(4-methoxy-phenyl)-2-ox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075428(1-(2-Methoxy-benzyl)-2-oxo-4-(3,4,5-trimethoxy-phe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075423(1-(2-Methoxy-benzyl)-4-(2-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075432(4-(4-Methoxy-phenyl)-2-oxo-1-(2,4,5-trimethoxy-ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075424(7-Methanesulfonylamino-1-(2-methoxy-benzyl)-4-(4-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075431(1-(4-Methoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075422(7-(Methanesulfonyl-propyl-amino)-1-(2-methoxy-benz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075421(7-(Ethyl-methanesulfonyl-amino)-1-(2-methoxy-benzy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075414(1-Benzyl-2-oxo-4-phenyl-1,2-dihydro-benzo[4,5]furo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075423(1-(2-Methoxy-benzyl)-4-(2-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50075429(7-(Methanesulfonyl-methyl-amino)-1-(2-methoxy-benz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50075431(1-(4-Methoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to displace [125I]-Endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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