Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50035043
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076948((R)-1-((3R,4R,4aR)-Decahydro-isoquinoline-1-carbon...)
Affinity DataIC50:  48nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076945((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076949((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076952(3-{[(S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076953((R)-1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carbo...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076951(((R)-2-Cyclohexyl-1-{methyl-[(2-oxo-1-piperidin-4-...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076946((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50:  590nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076954(((R)-2-Cyclohexyl-1-{[(2-oxo-1-piperidin-4-ylmethy...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076947((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076945((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076948((R)-1-((3R,4R,4aR)-Decahydro-isoquinoline-1-carbon...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076950(CHEMBL284008 | {(R)-2-Cyclohexyl-1-[(S)-1-(2-oxo-1...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076946((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076949((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076951(((R)-2-Cyclohexyl-1-{methyl-[(2-oxo-1-piperidin-4-...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076947((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076950(CHEMBL284008 | {(R)-2-Cyclohexyl-1-[(S)-1-(2-oxo-1...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076952(3-{[(S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076954(((R)-2-Cyclohexyl-1-{[(2-oxo-1-piperidin-4-ylmethy...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076953((R)-1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carbo...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataIC50:  1.34E+5nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed