Found 23 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50038001' 
Affinity DataKi: 4nMAssay Description:In vitro inhibition constant (Ki) against human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Affinity DataKi: 9.60nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human alpha-thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibitory activity against human thrombin (using Chromozym TH as the substrate)More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of bovine plasma thrombin using chromogenix AB as substrate after 30 secs by UV-spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibition against clot-associated thrombin.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human plasma thrombin using chromogenix AB as substrate after 30 secs by UV-spectrophotometryMore data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human thrombin using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substrate preincubated for 10 mins by spectrophotometer anal...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate incubated for 10 mins by fluorescence based microplate reader methodMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:In vitro inhibition of thrombin catalytic activity using s-2238 substrate at 10 uM was measured at rat after 3 min incubation with compoundMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:In vitro inhibitory activity against hydrolysis of human alpha thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibitory activity against thrombin induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 331nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
