Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50008868
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078072((S)-4-(4-(2-amino-6-methyl-4-oxo-4,7-dihydro-3H-py...)
Affinity DataIC50:  21nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18771((2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-...)
Affinity DataIC50:  36nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei TSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18771((2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-...)
Affinity DataIC50:  36nMAssay Description:Compound was evaluated for the inhibition at a given concentration against recombinant human TSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078072((S)-4-(4-(2-amino-6-methyl-4-oxo-4,7-dihydro-3H-py...)
Affinity DataIC50:  42nMAssay Description:Compound was evaluated for the inhibition at a given concentration against recombinant human Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50:  340nMAssay Description:Compound was evaluated for the inhibition at a given concentration against recombinant human Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078074(2-Amino-6-methyl-5-(pyridin-4-ylsulfanylmethyl)-3,...)
Affinity DataIC50: >2.50E+4nMAssay Description:Compound was evaluated for the inhibition at a given concentration against recombinant human Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078074(2-Amino-6-methyl-5-(pyridin-4-ylsulfanylmethyl)-3,...)
Affinity DataIC50: >2.60E+4nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078075((R)-2-{4-[(2-Amino-6-methyl-4-oxo-4,7-dihydro-3H-p...)
Affinity DataIC50:  9.00E+4nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50:  1.00E+5nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078076((R)-2-{4-[(2-Amino-6-methyl-4-oxo-4,7-dihydro-3H-p...)
Affinity DataIC50:  1.80E+5nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei TSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078076((R)-2-{4-[(2-Amino-6-methyl-4-oxo-4,7-dihydro-3H-p...)
Affinity DataIC50:  1.80E+5nMAssay Description:Compound was evaluated for the inhibition at a given concentration against recombinant human TSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078073((R)-2-(4-{[(2-Amino-6-methyl-4-oxo-4,7-dihydro-3H-...)
Affinity DataIC50:  3.60E+5nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed