Compile Data Set for Download or QSAR
Report error Found 93 Enz. Inhib. hit(s) with all data for entry = 1417
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11404(3-{[(2-methoxyethyl)(3-methoxypropyl)amino]methyl}...)
Affinity DataKi:  0.0800nM ΔG°:  -59.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11422(Compound 17m1 | 2-(3,4-Dimethoxyphenyl)-3-[(4-morp...)
Affinity DataKi:  0.0800nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11408(1,1-dioxo-3-[(prop-2-yn-1-ylamino)methyl]-2-propyl...)
Affinity DataKi:  0.100nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11399(Compound 17a7 | 3-{[(2-methoxyethyl)(prop-2-en-1-y...)
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11419(Compound 17j1 | 2-[(4-Methoxyphenyl)methyl]-3-[(4-...)
Affinity DataKi:  0.110nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11421(3-{[(2-hydroxyethyl)amino]methyl}-2-(3-methoxyphen...)
Affinity DataKi:  0.110nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11418(Compound 17i10 | 3-[(1-Imidazolyl)methyl]-2-(3-met...)
Affinity DataKi:  0.120nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11423(Compound 17n1 | 2-[4-(morpholin-4-yl)phenyl]-3-(mo...)
Affinity DataKi:  0.120nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKi:  0.130nM ΔG°:  -58.7kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11407(3-{[bis(2-methoxyethyl)amino]methyl}-1,1-dioxo-2-p...)
Affinity DataKi:  0.150nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11398(3-[N-(2-Methoxyethyl)-N-methylamino]methyl]-2-meth...)
Affinity DataKi:  0.150nM ΔG°:  -58.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11390(2-(3-hydroxyphenyl)-3-(morpholin-4-ylmethyl)-1,1-d...)
Affinity DataKi:  0.150nM ΔG°:  -58.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11391(2-(3-Methoxyphenyl)-3-[(4-morpholinyl)methyl]-2H-t...)
Affinity DataKi:  0.150nM ΔG°:  -58.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11411(3-(morpholin-4-ylmethyl)-1,1-dioxo-2-(prop-2-en-1-...)
Affinity DataKi:  0.160nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11425(2-(3-hydroxyphenyl)-1,1-dioxo-3-[(prop-2-yn-1-ylam...)
Affinity DataKi:  0.160nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11424(Compound 17o1 | 2-(3-Hydroxypropyl)-3-(4-morpholin...)
Affinity DataKi:  0.200nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11415(Compound 17h2 | 3-{[bis(2-methoxyethyl)amino]methy...)
Affinity DataKi:  0.210nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11400(2-Ethyl-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]...)
Affinity DataKi:  0.210nM ΔG°:  -57.5kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11401(2-Ethyl-3-[[bis(2-methoxyethyl)amino]methyl]-2H-th...)
Affinity DataKi:  0.210nM ΔG°:  -57.5kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11426(Compound 25 | 2-methyl-3-(morpholin-4-ylmethyl)-1,...)
Affinity DataKi:  0.210nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11414(Compound 17h1 | 2-(2-Methoxyethyl)-3-[(4-morpholin...)
Affinity DataKi:  0.220nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11403(2-[(2E)-4-(morpholin-4-yl)but-2-en-1-yl]-1,1-dioxo...)
Affinity DataKi:  0.240nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11395(Compound 5c | 2-[2-[4-Acetyl-(1-piperazinyl)]ethyl...)
Affinity DataKi:  0.25nM ΔG°:  -57.0kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11416(Compound 17i1 | 2-(3-Methoxypropyl)-3-[(4-morpholi...)
Affinity DataKi:  0.25nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11397(2-methyl-3-(morpholin-4-ylmethyl)-1,1-dioxo-2H-1,7...)
Affinity DataKi:  0.260nM ΔG°:  -56.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11417(3-[(cyclopropylamino)methyl]-2-(3-methoxypropyl)-1...)
Affinity DataKi:  0.260nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11406(Compound 17c1 | 3-[(4-Morpholinyl)methyl]-2-propyl...)
Affinity DataKi:  0.270nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11412(2-(cyclopropylmethyl)-3-(morpholin-4-ylmethyl)-1,1...)
Affinity DataKi:  0.300nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11413(Compound 17g1 | 2-cyclohexyl-3-(morpholin-4-ylmeth...)
Affinity DataKi:  0.310nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11394(Compound 5b | 2-[2-(4-Morpholinyl)ethyl]-2H-thieno...)
Affinity DataKi:  0.320nM ΔG°:  -56.4kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11409(Compound 17d1 | 2-(1-Methylethyl)-3-[(4-morpholiny...)
Affinity DataKi:  0.330nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11405(Compound 17b4 | 2-Ethyl-3-[[bis(2-hydroxyethyl)ami...)
Affinity DataKi:  0.330nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11393(2-{2-[bis(2-methoxyethyl)amino]ethyl}-1,1-dioxo-2H...)
Affinity DataKi:  0.340nM ΔG°:  -56.2kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11410(Compound 17d8 | 1,1-dioxo-3-[(prop-2-yn-1-ylamino)...)
Affinity DataKi:  0.470nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  0.510nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11396(2-[2-(Propylamino)ethyl]-2H-thieno[3,2-e]-1,2-thia...)
Affinity DataKi:  0.520nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11425(2-(3-hydroxyphenyl)-1,1-dioxo-3-[(prop-2-yn-1-ylam...)
Affinity DataIC50: 0.600nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11413(Compound 17g1 | 2-cyclohexyl-3-(morpholin-4-ylmeth...)
Affinity DataIC50: 0.790nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11394(Compound 5b | 2-[2-(4-Morpholinyl)ethyl]-2H-thieno...)
Affinity DataIC50: 0.820nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11393(2-{2-[bis(2-methoxyethyl)amino]ethyl}-1,1-dioxo-2H...)
Affinity DataIC50: 0.910nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11405(Compound 17b4 | 2-Ethyl-3-[[bis(2-hydroxyethyl)ami...)
Affinity DataIC50: 0.960nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11395(Compound 5c | 2-[2-[4-Acetyl-(1-piperazinyl)]ethyl...)
Affinity DataIC50: 0.960nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11411(3-(morpholin-4-ylmethyl)-1,1-dioxo-2-(prop-2-en-1-...)
Affinity DataIC50: 0.990nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11401(2-Ethyl-3-[[bis(2-methoxyethyl)amino]methyl]-2H-th...)
Affinity DataIC50: 1.04nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11422(Compound 17m1 | 2-(3,4-Dimethoxyphenyl)-3-[(4-morp...)
Affinity DataIC50: 1.05nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11400(2-Ethyl-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]...)
Affinity DataIC50: 1.11nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11399(Compound 17a7 | 3-{[(2-methoxyethyl)(prop-2-en-1-y...)
Affinity DataIC50: 1.11nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11390(2-(3-hydroxyphenyl)-3-(morpholin-4-ylmethyl)-1,1-d...)
Affinity DataIC50: 1.15nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11421(3-{[(2-hydroxyethyl)amino]methyl}-2-(3-methoxyphen...)
Affinity DataIC50: 1.16nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11398(3-[N-(2-Methoxyethyl)-N-methylamino]methyl]-2-meth...)
Affinity DataIC50: 1.17nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
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