Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 10980
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581953BDBM581953(WO2023004291, Compound CDD-1819)
Affinity DataKi:  4.90nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581952BDBM581952(WO2023004291, Compound CDD-1830)
Affinity DataKi:  5.60nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581948BDBM581948(WO2023004291, Compound CDD-1733)
Affinity DataKi:  12nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581950BDBM581950(WO2023004291, Compound CDD-1780)
Affinity DataKi:  14nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab-His6(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581944BDBM581944(WO2023004291, Compound CDD-1714)
Affinity DataKi:  20nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581944BDBM581944(WO2023004291, Compound CDD-1714)
Affinity DataKi:  24nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581951BDBM581951(WO2023004291, Compound CDD-1795)
Affinity DataKi:  29nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab-His6(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 484197BDBM484197(CDD-1976 | WO2023004291, Compound CDD-1976)
Affinity DataKi:  37nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 484197BDBM484197(CDD-1976 | WO2023004291, Compound CDD-1976)
Affinity DataKi:  42nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab-His6(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 484196BDBM484196(CDD-1713 | WO2023004291, Compound CDD-1713)
Affinity DataKi:  45nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581949BDBM581949(WO2023004291, Compound CDD-1829)
Affinity DataKi:  46nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 484196BDBM484196(CDD-1713 | WO2023004291, Compound CDD-1713)
Affinity DataKi:  65nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab-His6(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581945BDBM581945(WO2023004291, Compound CDD-1886)
Affinity DataKi:  1.57E+4nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

WIPO
LigandChemical structure of BindingDB Monomer ID 581945BDBM581945(WO2023004291, Compound CDD-1886)
Affinity DataKi:  2.12E+4nMAssay Description:To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2023004291