Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 313
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 348BDBM348(1-Valine Methylamide deriv. 1 | Diol-Based HIV-1 p...)
Affinity DataKi:  0.800nM ΔG°:  -52.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 353BDBM353((2R,3R,4R,5R)-2,5-bis[(2,4-difluorophenyl)methoxy]...)
Affinity DataKi:  1.12nM ΔG°:  -51.9kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 358BDBM358(symmetric/asymmetric inhibitor 2 | (2R,3R,4R,5R)-2...)
Affinity DataKi:  1.22nM ΔG°:  -51.7kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 352BDBM352(N1,N6-Bis-[(1S)-2-methyl-1-(methylcarbamoyl)propyl...)
Affinity DataKi:  1.28nM ΔG°:  -51.6kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 365BDBM365(N1,N6-Bis-[(2R)-hydroxy-1(S)-indanyl]-(2R,3R,4R,5R...)
Affinity DataKi:  1.64nM ΔG°:  -51.0kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 363BDBM363(N1,N6-Bis-[(2R)-hydroxy-1(S)-indanyl]-(2R,3R,4R,5R...)
Affinity DataKi:  1.65nM ΔG°:  -51.0kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 355BDBM355((2R,3R,4R,5R)-2,5-bis[(2,6-difluorophenyl)methoxy]...)
Affinity DataKi:  1.73nM ΔG°:  -50.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 351BDBM351(N1,N6-Bis-[(1S)-2-methyl-1-(methylcarbamoyl)propyl...)
Affinity DataKi:  1.79nM ΔG°:  -50.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 350BDBM350(N1,N6-Bis-[(1S)-2-methyl-1-(methylcarbamoyl)propyl...)
Affinity DataKi:  1.83nM ΔG°:  -50.7kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 349BDBM349((2R,3R,4R,5R)-2,5-bis[(2-fluorophenyl)methoxy]-3,4...)
Affinity DataKi:  1.92nM ΔG°:  -50.6kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 354BDBM354((2R,3R,4R,5R)-2,5-bis[(2,5-difluorophenyl)methoxy]...)
Affinity DataKi:  1.98nM ΔG°:  -50.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 356BDBM356(N1,N6-Bis-[(1S)-2-methyl-1-(methylcarbamoyl)propyl...)
Affinity DataKi:  1.98nM ΔG°:  -50.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 357BDBM357((2R,3R,4R,5R)-2,5-bis[(3,5-difluorophenyl)methoxy]...)
Affinity DataKi:  1.98nM ΔG°:  -50.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 359BDBM359((2R,3R,4R,5R)-2,5-bis[(2-fluorophenyl)methoxy]-3,4...)
Affinity DataKi:  3.26nM ΔG°:  -49.3kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 364BDBM364((2R,3R,4R,5R)-2,5-bis[(2,5-difluorophenyl)methoxy]...)
Affinity DataKi:  3.29nM ΔG°:  -49.2kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 366BDBM366(N1,N6-Bis-[(2R)-hydroxy-1(S)-indanyl]-(2R,3R,4R,5R...)
Affinity DataKi:  3.90nM ΔG°:  -48.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 362BDBM362(N1,N6-Bis-[(2R)-hydroxy-1(S)-indanyl]-(2R,3R,4R,5R...)
Affinity DataKi:  4nM ΔG°:  -48.7kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 367BDBM367((2R,3R,4R,5R)-2,5-bis[(3,5-difluorophenyl)methoxy]...)
Affinity DataKi:  5nM ΔG°:  -48.2kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 361BDBM361((2R,3R,4R,5R)-2,5-bis[(4-fluorophenyl)methoxy]-3,4...)
Affinity DataKi:  5.39nM ΔG°:  -48.0kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandChemical structure of BindingDB Monomer ID 360BDBM360((2R,3R,4R,5R)-2,5-bis[(3-fluorophenyl)methoxy]-3,4...)
Affinity DataKi:  7.13nM ΔG°:  -47.3kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed