Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50011382
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105970BDBM50105970(4-{N'-[1-(4-tert-Butyl-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  20nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105947BDBM50105947(3-Hydroxy-4-{N'-[3-methyl-5-oxo-1-(3-trifluorometh...)
Affinity DataEC50:  40nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105963BDBM50105963(4-{N'-[1-(3,4-Dimethyl-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  40nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105942BDBM50105942(4-{N'-[1-(3-tert-Butyl-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  70nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105976BDBM50105976(3-Hydroxy-4-(1-hydroxy-naphthalen-2-ylazo)-naphtha...)
Affinity DataEC50:  70nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105962BDBM50105962(3-Hydroxy-4-{N'-[1-(4-isopropyl-phenyl)-3-methyl-5...)
Affinity DataEC50:  70nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105940BDBM50105940(4-{N'-[1-(3,4-Dimethyl-phenyl)-5-oxo-1,5-dihydro-p...)
Affinity DataEC50:  100nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105966BDBM50105966(3-Hydroxy-4-{N'-[3-methyl-5-oxo-1-(4-trifluorometh...)
Affinity DataEC50:  100nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105950BDBM50105950(4-{N'-[1-(3,4-Dichloro-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105977BDBM50105977(3-Hydroxy-4-(2-hydroxy-naphthalen-1-ylazo)-naphtha...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105937BDBM50105937(3-Hydroxy-4-(10-hydroxy-phenanthren-9-ylazo)-napht...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105954BDBM50105954(1-(4-tert-Butyl-phenyl)-4-[(2-hydroxy-4-sulfo-naph...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105969BDBM50105969(4-{N'-[1-(4-Benzyloxy-phenyl)-3-methyl-5-oxo-1,5-d...)
Affinity DataEC50:  200nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105961BDBM50105961(3-Hydroxy-4-(2-hydroxy-7-methoxy-naphthalen-1-ylaz...)
Affinity DataEC50:  300nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105967BDBM50105967(3-Hydroxy-4-{N'-[1-(4-iodo-phenyl)-3-methyl-5-oxo-...)
Affinity DataEC50:  300nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105973BDBM50105973(4-{N'-[3-tert-Butyl-1-(3,4-dimethyl-phenyl)-5-oxo-...)
Affinity DataEC50:  300nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105972BDBM50105972(3-Hydroxy-4-{N'-[3-methyl-1-(3-nitro-phenyl)-5-oxo...)
Affinity DataEC50:  300nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105959BDBM50105959(3-Hydroxy-4-{N'-[3-methyl-1-(4-nitro-phenyl)-5-oxo...)
Affinity DataEC50:  400nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105952BDBM50105952(4-{N'-[1-(4-Fluoro-phenyl)-3-methyl-5-oxo-1,5-dihy...)
Affinity DataEC50:  500nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105938BDBM50105938(4-{N'-[1-(3,4-Dimethyl-phenyl)-3-ethoxy-5-oxo-1,5-...)
Affinity DataEC50:  600nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105960BDBM50105960(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-m-tolyl-1,5-dihy...)
Affinity DataEC50:  700nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105946BDBM50105946(4-{N'-[1-(3,4-Dimethyl-phenyl)-5-oxo-3-phenyl-1,5-...)
Affinity DataEC50:  900nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105965BDBM50105965(4-{N'-[1-(3,4-Dimethyl-phenyl)-3-methyl-5-oxo-1,5-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105979BDBM50105979(1-(4-tert-Butyl-phenyl)-4-[(2-hydroxy-4-sulfo-naph...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105948BDBM50105948(4-{N'-[1-(3-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105958BDBM50105958(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-p-tolyl-1,5-dihy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105941BDBM50105941(4-(2,3-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105953BDBM50105953(4-(2,7-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105936BDBM50105936(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-phenyl-1,5-dihyd...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105951BDBM50105951(4-(2,6-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105945BDBM50105945(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-p-tolyl-1,5-dihy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105968BDBM50105968(4-{N'-[1-(4-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105944BDBM50105944(3-Hydroxy-4-(2-hydroxy-5-methyl-phenylazo)-naphtha...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105974BDBM50105974(3-Hydroxy-4-(4-hydroxy-2-methoxy-naphthalen-1-ylaz...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105975BDBM50105975(3-Hydroxy-4-{N'-[1-(4-methanesulfonyl-phenyl)-3-me...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105949BDBM50105949(4-(2,4-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105980BDBM50105980(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-phenyl-1,5-dihyd...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105957BDBM50105957(4-{N'-[3-Amino-1-(4-tert-butyl-phenyl)-5-oxo-1,5-d...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105964BDBM50105964(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-pyridin-2-yl-1,5...)
Affinity DataEC50:  7.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105955BDBM50105955(3-Hydroxy-4-{N'-[3-methyl-1-(2-nitro-phenyl)-5-oxo...)
Affinity DataEC50:  8.00E+3nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105978BDBM50105978(4-{N'-[1-(3-Ethylsulfamoyl-phenyl)-3-methyl-5-oxo-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105939BDBM50105939(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-o-tolyl-1,5-dihy...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105956BDBM50105956(3-Hydroxy-4-(2-hydroxy-4-sulfo-naphthalen-1-ylazo)...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105943BDBM50105943(4-[N'-(1-Benzyl-3-methyl-5-oxo-1,5-dihydro-pyrazol...)
Affinity DataEC50: >3.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105971BDBM50105971(4-{N'-[1-(2-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...)
Affinity DataEC50: >3.00E+4nMAssay Description:Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed