Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50011435
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106517BDBM50106517(6-(4-Bromo-thiophen-2-ylmethoxy)-9H-purin-2-ylamin...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106510BDBM50106510(2-{12-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pu...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106518BDBM50106518(2-{10-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pu...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106511BDBM50106511(2-{8-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50: 32nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106515BDBM50106515(7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106514BDBM50106514(2-{4-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106512BDBM50106512(2-{6-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50: 450nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106513BDBM50106513(2-{4-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50: 450nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5491BDBM5491(6-(benzyloxy)-9H-purin-2-amine | CHEMBL407874 | O6...)
Affinity DataIC50: 620nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106509BDBM50106509(2-{2-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50: 680nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106519BDBM50106519(2-[2-(5-Amino-7-benzyloxy-[1,2,3]triazolo[4,5-d]py...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
German Cancer Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106516BDBM50106516(2-[2-(2-Amino-6-benzyloxy-purin-9-yl)-ethoxy]-6-hy...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed