Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50011651
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057581(4-(4-Fluoro-5-phenyl-3-trifluoromethyl-pyrazol-1-y...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057618(4-[5-(3-Methyl-4-methylsulfanyl-phenyl)-3-trifluor...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057551(4-[5-(4-Dimethylamino-phenyl)-3-trifluoromethyl-py...)
Affinity DataIC50:  4.70nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057606(4-[4-Chloro-5-(4-chloro-phenyl)-3-trifluoromethyl-...)
Affinity DataIC50:  5.30nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057575(4-[5-(4-Dimethylamino-3-fluoro-phenyl)-3-trifluoro...)
Affinity DataIC50:  5.70nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057589(4-[5-(4-Methoxy-phenyl)-3-trifluoromethyl-pyrazol-...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057591(4-[5-(4-Methylsulfanyl-phenyl)-3-trifluoromethyl-p...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057620(4-[5-(4-Methoxy-3-methyl-phenyl)-3-trifluoromethyl...)
Affinity DataIC50:  9.30nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057572(4-[4-Chloro-5-(4-chloro-phenyl)-3-cyano-pyrazol-1-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057527(4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057560(4-[5-(3,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057573(4-[5-(4-Methylamino-phenyl)-3-trifluoromethyl-pyra...)
Affinity DataIC50:  16nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057553(4-[5-(4-Chloro-phenyl)-4-methyl-3-trifluoromethyl-...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057541(4-[5-(3-Chloro-4-methylamino-phenyl)-3-trifluorome...)
Affinity DataIC50:  27nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057528(4-[5-(4-Chloro-phenyl)-4-ethyl-3-trifluoromethyl-p...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057535(4-(4-Chloro-3-methyl-5-phenyl-pyrazol-1-yl)-benzen...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057590(4-[4-Bromo-5-(4-chloro-phenyl)-pyrazol-1-yl]-benze...)
Affinity DataIC50:  31nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057518(4-(5-Phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzen...)
Affinity DataIC50:  32nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057564(4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  41nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057566(4-(4-Chloro-5-phenyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50:  49nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057601(4-[5-(2-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057569(4-[5-(2,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057546(4-[5-(2-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  58nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057522(4-[5-(3-Chloro-4-methoxy-5-methyl-phenyl)-3-triflu...)
Affinity DataIC50:  66nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057539(4-(5-o-Tolyl-3-trifluoromethyl-pyrazol-1-yl)-benze...)
Affinity DataIC50:  69nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057548(4-(4-Cyano-5-p-tolyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50:  76nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057530(4-(4-Methoxy-5-phenyl-3-trifluoromethyl-pyrazol-1-...)
Affinity DataIC50:  80nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057567(4-(5-m-Tolyl-3-trifluoromethyl-pyrazol-1-yl)-benze...)
Affinity DataIC50:  110nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057525(4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057555(4-[5-(2-Methoxy-phenyl)-3-trifluoromethyl-pyrazol-...)
Affinity DataIC50:  290nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057579(4-[3-Cyano-5-(4-fluoro-phenyl)-pyrazol-1-yl]-benze...)
Affinity DataIC50:  340nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057604(4-[4-Chloro-5-(4-chloro-phenyl)-3-hydroxymethyl-py...)
Affinity DataIC50:  340nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057597(4-[5-(4-Amino-phenyl)-3-trifluoromethyl-pyrazol-1-...)
Affinity DataIC50:  340nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057613(4-[5-(3-Ethyl-4-methoxy-phenyl)-3-trifluoromethyl-...)
Affinity DataIC50:  430nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057607(4-[5-(3,4-Dimethoxy-phenyl)-3-trifluoromethyl-pyra...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057524(4-[5-(4-Chloro-phenyl)-3-hydroxymethyl-pyrazol-1-y...)
Affinity DataIC50:  830nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057531(4-[5-(4-Ethyl-phenyl)-3-trifluoromethyl-pyrazol-1-...)
Affinity DataIC50:  860nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057587(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057574(4-[5-(4-Nitro-phenyl)-3-trifluoromethyl-pyrazol-1-...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057556(4-(4-Hydroxy-5-phenyl-3-trifluoromethyl-pyrazol-1-...)
Affinity DataIC50:  3.58E+3nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057536(4-(4-Fluoro-5-phenyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50:  4.66E+3nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057616(4-[5-(3-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  7.73E+3nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057568(4-(3-(trifluoromethyl)-5-(4-(trifluoromethyl)pheny...)
Affinity DataIC50:  8.23E+3nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057517(4-[5-(2-Dimethylamino-phenyl)-3-trifluoromethyl-py...)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057521(4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057565(4-(4-Amino-5-phenyl-pyrazol-1-yl)-benzenesulfonami...)
Affinity DataIC50:  2.97E+4nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057595(4-(4-Methyl-5-phenyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50:  4.71E+4nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057599(4-(3-Methyl-5-phenyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50:  6.28E+4nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50057538(4-[5-(4-Hydroxymethyl-phenyl)-3-trifluoromethyl-py...)
Affinity DataIC50:  9.33E+4nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed