Compile Data Set for Download or QSAR
Report error Found 102 Enz. Inhib. hit(s) with all data for entry = 50011761
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110227(CHEMBL267434 | CHEMBL2332368 | 3-{2-[4-(4-Methyl-p...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110228(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110236(3-(3,5-Dichloro-phenyl)-3-{2-[5-(4-methyl-pyridin-...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110232(3-Biphenyl-4-yl-3-{2-[5-(pyridin-2-ylamino)-pentan...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110232(3-Biphenyl-4-yl-3-{2-[5-(pyridin-2-ylamino)-pentan...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110230([5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-me...)
Affinity DataIC50: 3nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110233([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 3nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 3nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110231(3-(3-Nitro-phenyl)-3-{2-[4-(pyridin-2-ylamino)-but...)
Affinity DataIC50: 4nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-5-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50: 4nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50: 6nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110227(CHEMBL267434 | CHEMBL2332368 | 3-{2-[4-(4-Methyl-p...)
Affinity DataIC50: 8nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110234([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-10-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110231(3-(3-Nitro-phenyl)-3-{2-[4-(pyridin-2-ylamino)-but...)
Affinity DataIC50: 13nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110228(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50: 14nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110226([5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6...)
Affinity DataIC50: 24nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50100144(3-({[2-(5-{[(Z)-amino(imino)methyl]amino}pentanoyl...)
Affinity DataIC50: 26nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110228(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50: 30nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110230([5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-me...)
Affinity DataIC50: 37nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110228(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50: 39nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50100144(3-({[2-(5-{[(Z)-amino(imino)methyl]amino}pentanoyl...)
Affinity DataIC50: 40nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110234([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-10-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110231(3-(3-Nitro-phenyl)-3-{2-[4-(pyridin-2-ylamino)-but...)
Affinity DataIC50: 42nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50: 44nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 45nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50: 53nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110236(3-(3,5-Dichloro-phenyl)-3-{2-[5-(4-methyl-pyridin-...)
Affinity DataIC50: 53nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-5-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50: 53nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50: 61nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50: 64nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110231(3-(3-Nitro-phenyl)-3-{2-[4-(pyridin-2-ylamino)-but...)
Affinity DataIC50: 90nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110232(3-Biphenyl-4-yl-3-{2-[5-(pyridin-2-ylamino)-pentan...)
Affinity DataIC50: 100nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110227(CHEMBL267434 | CHEMBL2332368 | 3-{2-[4-(4-Methyl-p...)
Affinity DataIC50: 200nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110236(3-(3,5-Dichloro-phenyl)-3-{2-[5-(4-methyl-pyridin-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50: 300nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110236(3-(3,5-Dichloro-phenyl)-3-{2-[5-(4-methyl-pyridin-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110230([5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-me...)
Affinity DataIC50: 400nMAssay Description:Inhibition of integrin alpha-v/beta-5 mediated UCLAP-3 cell adhesion on vitronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110230([5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-me...)
Affinity DataIC50: 400nMAssay Description:Inhibition of integrin alpha-v/beta-3 mediated M21 cell adhesion to vitronectin with monoclonal antibody P1F6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50100144(3-({[2-(5-{[(Z)-amino(imino)methyl]amino}pentanoyl...)
Affinity DataIC50: 460nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110230([5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-me...)
Affinity DataIC50: 470nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110235([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 530nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110233([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-3,6...)
Affinity DataIC50: 540nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50: 580nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110230([5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-me...)
Affinity DataIC50: 590nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110226([5-Benzyl-11-(3-guanidino-propyl)-7,8-dimethyl-3,6...)
Affinity DataIC50: 662nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110234([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-10-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50100174(3-Biphenyl-4-yl-5-{N'-[5-(4-methyl-pyridin-2-ylami...)
Affinity DataIC50: 970nMAssay Description:Inhibition of integrin alpha-v/beta-3 mediated M21 cell adhesion to vitronectin with monoclonal antibody P1F6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50100144(3-({[2-(5-{[(Z)-amino(imino)methyl]amino}pentanoyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110231(3-(3-Nitro-phenyl)-3-{2-[4-(pyridin-2-ylamino)-but...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of integrin alpha-v/beta-5 mediated UCLAP-3 cell adhesion on vitronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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