Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50011938
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  22nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50:  220nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50:  420nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50:  440nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112313(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-eth...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of Escherichia coli thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112313(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-eth...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of rocombinant human thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of Escherichia coli thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112312(2-({4-[1-(4,6-Diamino-furo[2,3-b]pyridin-3-ylmethy...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of recombinant human thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: >3.60E+5nMAssay Description:Inhibition of rh thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed