Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50003609
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473748BDBM50473748(CHEMBL313982)
Affinity DataIC50: 0.501nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473722BDBM50473722(CHEMBL315565)
Affinity DataIC50: 0.631nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473753BDBM50473753(CHEMBL314938)
Affinity DataIC50: 3.20nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473750BDBM50473750(CHEMBL312868)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473745BDBM50473745(CHEMBL87412)
Affinity DataIC50: 6.30nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473744BDBM50473744(CHEMBL316016)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473754BDBM50473754(CHEMBL315934)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473739BDBM50473739(CHEMBL85753)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473743BDBM50473743(CHEMBL86145)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064858BDBM50064858(4-[2-(3-Cyclopentyloxy-4-methoxy-phenyl)-2-phenyl-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473751BDBM50473751(CHEMBL85895)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473757BDBM50473757(CHEMBL315248)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304391BDBM50304391((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473749BDBM50473749(CHEMBL312799)
Affinity DataIC50: 79nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473755BDBM50473755(CHEMBL312666)
Affinity DataIC50: 79nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346088BDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30126BDBM30126(CHEMBL313041 | phthalazinone, 19)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473351BDBM50473351(CHEMBL85424)
Affinity DataIC50: 126nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473742BDBM50473742(CHEMBL86158)
Affinity DataIC50: 126nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473740BDBM50473740(CHEMBL85197)
Affinity DataIC50: 158nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473746BDBM50473746(CHEMBL83813)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473756BDBM50473756(CHEMBL312212)
Affinity DataIC50: 251nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365055BDBM50365055(CHEMBL82318)
Affinity DataIC50: 398nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473752BDBM50473752(CHEMBL312101)
Affinity DataIC50: 794nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473741BDBM50473741(CHEMBL81896)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473747BDBM50473747(CHEMBL315264)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473758BDBM50473758(CHEMBL84779)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 carried out in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed