Compile Data Set for Download or QSAR
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Found 41 Enz. Inhib. hit(s) with all data for entry = 50012206
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116042(CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116048(CHEMBL67828 | {6-Nitro-2,3-dioxo-7-[3-(4-phenethyl...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  46nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116046(CHEMBL12465 | [7-(3-Aminomethyl-pyrrol-1-yl)-6-nit...)
Affinity DataKi:  230nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116044(CHEMBL416685 | {6-Nitro-2,3-dioxo-7-[3-(4-phenyl-p...)
Affinity DataKi:  230nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116047((6-Nitro-2,3-dioxo-7-{3-[(3-phenyl-propylamino)-me...)
Affinity DataKi:  320nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116041(CHEMBL303415 | [6-Nitro-2,3-dioxo-7-(3-piperidin-1...)
Affinity DataKi:  330nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116045(3-(7-{3-[(Benzyl-methyl-amino)-methyl]-pyrrol-1-yl...)
Affinity DataKi:  430nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116044(CHEMBL416685 | {6-Nitro-2,3-dioxo-7-[3-(4-phenyl-p...)
Affinity DataKi:  530nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116049((6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-qu...)
Affinity DataKi:  530nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  610nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116042(CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...)
Affinity DataKi:  680nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116043(3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116049((6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-qu...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity towards cloned human Kai-2 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116048(CHEMBL67828 | {6-Nitro-2,3-dioxo-7-[3-(4-phenethyl...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116047((6-Nitro-2,3-dioxo-7-{3-[(3-phenyl-propylamino)-me...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116048(CHEMBL67828 | {6-Nitro-2,3-dioxo-7-[3-(4-phenethyl...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116050(1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116046(CHEMBL12465 | [7-(3-Aminomethyl-pyrrol-1-yl)-6-nit...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116043(3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116043(3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116044(CHEMBL416685 | {6-Nitro-2,3-dioxo-7-[3-(4-phenyl-p...)
Affinity DataKi:  3.60E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116049((6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-qu...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116042(CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116050(1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116041(CHEMBL303415 | [6-Nitro-2,3-dioxo-7-(3-piperidin-1...)
Affinity DataKi:  5.70E+3nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116050(1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataKi:  5.80E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116047((6-Nitro-2,3-dioxo-7-{3-[(3-phenyl-propylamino)-me...)
Affinity DataKi:  6.20E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116046(CHEMBL12465 | [7-(3-Aminomethyl-pyrrol-1-yl)-6-nit...)
Affinity DataKi:  9.80E+3nMAssay Description:Binding affinity of the compound was determined towards Kai-2 using [3]H-kainate as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116050(1-(4-Carboxymethyl-7-nitro-2,3-dioxo-1,2,3,4-tetra...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity of the compound was determined towards Kai-2 using [3]H-kainate as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity of the compound was determined towards Kai-2 using [3]H-kainate as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116044(CHEMBL416685 | {6-Nitro-2,3-dioxo-7-[3-(4-phenyl-p...)
Affinity DataKi:  1.80E+4nMAssay Description:Binding affinity towards cloned human Kai-2 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116047((6-Nitro-2,3-dioxo-7-{3-[(3-phenyl-propylamino)-me...)
Affinity DataKi:  2.00E+4nMAssay Description:Binding affinity towards cloned human Kai-2 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116042(CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...)
Affinity DataKi:  2.00E+4nMAssay Description:Binding affinity towards cloned human Kai-2 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116045(3-(7-{3-[(Benzyl-methyl-amino)-methyl]-pyrrol-1-yl...)
Affinity DataKi:  2.30E+4nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116043(3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-...)
Affinity DataKi:  2.50E+4nMAssay Description:Binding affinity towards cloned human Kai-2 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116048(CHEMBL67828 | {6-Nitro-2,3-dioxo-7-[3-(4-phenethyl...)
Affinity DataKi:  2.50E+4nMAssay Description:Binding affinity towards cloned human Kai-2 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116041(CHEMBL303415 | [6-Nitro-2,3-dioxo-7-(3-piperidin-1...)
Affinity DataKi:  2.80E+4nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116041(CHEMBL303415 | [6-Nitro-2,3-dioxo-7-(3-piperidin-1...)
Affinity DataKi: >3.00E+4nMAssay Description:Binding affinity towards cloned human Kai-2 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116045(3-(7-{3-[(Benzyl-methyl-amino)-methyl]-pyrrol-1-yl...)
Affinity DataKi: >3.00E+4nMAssay Description:Binding affinity towards cloned human Kai-2 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed