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Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50012643
TargetEstrogen receptor(Human)
Free University of Berlin

Curated by ChEMBL
LigandPNGBDBM50121319(4-(1,2-Diphenyl-but-1-enyl)-phenol | CHEMBL50995)
Affinity DataIC50:  7nMAssay Description:Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Free University of Berlin

Curated by ChEMBL
LigandPNGBDBM50121320(4-[4,4,4-trifluoro-1-(4-hydroxyphenyl)-2-phenylbut...)
Affinity DataIC50:  9nMAssay Description:Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Free University of Berlin

Curated by ChEMBL
LigandPNGBDBM50121317(1,1-bis(4,4'-hydroxyphenyl)-2-phenylbut-1-ene | 4,...)
Affinity DataIC50:  15nMAssay Description:Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Free University of Berlin

Curated by ChEMBL
LigandPNGBDBM50121322(4-[1-(4-hydroxyphenyl)-2-phenylprop-1-enyl]phenol ...)
Affinity DataIC50:  30nMAssay Description:Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Free University of Berlin

Curated by ChEMBL
LigandPNGBDBM50121321(4-[1-(4-hydroxyphenyl)-2-phenylpent-1-enyl]phenol ...)
Affinity DataIC50:  50nMAssay Description:Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Free University of Berlin

Curated by ChEMBL
LigandPNGBDBM50023749(4-(1,2-diphenyl-vinyl)-phenol | 4-[1-(4-hydroxyphe...)
Affinity DataIC50:  150nMAssay Description:Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetEstrogen receptor(Human)
Free University of Berlin

Curated by ChEMBL
LigandPNGBDBM50121318(4-[1-(4-hydroxyphenyl)-2-phenylhex-1-enyl]phenol |...)
Affinity DataIC50:  500nMAssay Description:Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Free University of Berlin

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  500nMAssay Description:Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed