Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 2279 Sort by
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18864(3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...)
Affinity DataIC50: 0.0190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50: 0.0250nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18864(3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...)
Affinity DataIC50: 0.0410nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)
Affinity DataIC50: 0.0480nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18867(dibromo phenylacetic acid, 11a | 2-{3,5-dibromo-4-...)
Affinity DataIC50: 0.0950nM EC50:  0.200nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50: 0.100nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 0.110nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)
Affinity DataIC50: 0.140nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 0.140nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18870(3-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 0.150nM EC50:  0.280nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataIC50: 0.240nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataIC50: 0.260nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18870(3-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 0.760nM EC50:  0.300nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 1.10nM EC50:  3.5nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18867(dibromo phenylacetic acid, 11a | 2-{3,5-dibromo-4-...)
Affinity DataIC50: 1.40nM EC50:  0.380nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18866(3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]be...)
Affinity DataIC50: 2.10nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18866(3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]be...)
Affinity DataIC50: 9.70nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)
Affinity DataIC50: 21nM EC50:  150nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 25nM EC50:  11nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)
Affinity DataIC50: 130nM EC50:  190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed