Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50003636
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474160(CHEMBL61699)
Affinity DataIC50: 2nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474164(CHEMBL304715)
Affinity DataIC50: 2.5nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474171(CHEMBL62131)
Affinity DataIC50: 4nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474161(CHEMBL64824)
Affinity DataIC50: 4nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474165(CHEMBL60026)
Affinity DataIC50: 4nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474159(CHEMBL64052)
Affinity DataIC50: 6.30nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474163(CHEMBL64544)
Affinity DataIC50: 6.30nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474162(CHEMBL59953)
Affinity DataIC50: 7.90nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474168(CHEMBL294327)
Affinity DataIC50: 7.90nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474157(CHEMBL293589)
Affinity DataIC50: 7.90nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50228247(LY-197055 | CHEMBL38017)
Affinity DataIC50: 13nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474154(CHEMBL60839)
Affinity DataIC50: 13nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474166(CHEMBL60999)
Affinity DataIC50: 16nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474155(CHEMBL61116)
Affinity DataIC50: 16nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474167(CHEMBL61822)
Affinity DataIC50: 16nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474170(CHEMBL303550)
Affinity DataIC50: 20nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474155(CHEMBL61116)
Affinity DataIC50: 32nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474160(CHEMBL61699)
Affinity DataIC50: 79nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474156(CHEMBL59996)
Affinity DataIC50: 79nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474158(CHEMBL61667)
Affinity DataIC50: 79nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474158(CHEMBL61667)
Affinity DataIC50: 100nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474159(CHEMBL64052)
Affinity DataIC50: 100nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50: 100nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474169(LY-264233 | CHEMBL432717)
Affinity DataIC50: 126nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM14769(6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydr...)
Affinity DataIC50: 158nMAssay Description:inhibition of cAMP-specific phosphodiesterase 4 (PDE4) was determined in cytosol from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474161(CHEMBL64824)
Affinity DataIC50: 200nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474171(CHEMBL62131)
Affinity DataIC50: 200nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474164(CHEMBL304715)
Affinity DataIC50: 200nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474157(CHEMBL293589)
Affinity DataIC50: 251nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474167(CHEMBL61822)
Affinity DataIC50: 501nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50016839(CHEMBL282765 | 5-Methyl-6-[4-(4,5,6,7-tetrahydro-b...)
Affinity DataIC50: 501nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM14769(6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydr...)
Affinity DataIC50: 631nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474163(CHEMBL64544)
Affinity DataIC50: 794nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474162(CHEMBL59953)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474165(CHEMBL60026)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474168(CHEMBL294327)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474156(CHEMBL59996)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474154(CHEMBL60839)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474166(CHEMBL60999)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474170(CHEMBL303550)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed