Compile Data Set for Download or QSAR
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Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50037168
TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130785(CHEMBL542453 | CHEMBL609978 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  1.90nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128054(Allyl-{6-[1-(4-bromo-phenyl)-isoquinolin-6-yloxy]-...)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130788(CHEMBL116705 | CHEMBL611484 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  4.10nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128055(Allyl-{6-[4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazi...)
Affinity DataIC50:  4.10nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130783(CHEMBL115020 | CHEMBL611485 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  4.60nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128050(CHEMBL114259 | CHEMBL416694 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  5.40nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130789(Allyl-{6-[3-(4-bromo-phenyl)-benzo[b]thiophen-6-yl...)
Affinity DataIC50:  5.60nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130786(CHEMBL115923 | CHEMBL611486 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  6.20nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130774(CHEMBL115375 | CHEMBL611757 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  6.30nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  6.5nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130775(CHEMBL554209 | CHEMBL611758 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  6.70nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130772(Allyl-{6-[3-(4-bromo-phenyl)-1,1-dioxo-1H-1lambda*...)
Affinity DataIC50:  7.80nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130784(Allyl-{6-[1-(4-bromo-phenyl)-3,4-dihydro-isoquinol...)
Affinity DataIC50:  7.90nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130787(CHEMBL114266 | CHEMBL612025 | {6-[6-(Allyl-methyl-...)
Affinity DataIC50:  8.70nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130776(Allyl-{6-[4-(4-bromo-phenyl)-2H-chromen-7-yloxy]-h...)
Affinity DataIC50:  11.4nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130781(Allyl-{6-[4-(4-bromo-phenyl)-quinazolin-7-yloxy]-h...)
Affinity DataIC50:  12.3nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130777((4-Bromo-phenyl)-(4-{6-[(3-hydroxy-propyl)-methyl-...)
Affinity DataIC50:  15.7nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128058(ALLYL-{6-[3-(4-BROMO-PHENYL)-1-METHYL-1H-INDAZOL-6...)
Affinity DataIC50:  19.6nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130779(CHEMBL553281 | CHEMBL611755 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  22.5nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130771((4-Bromo-phenyl)-{4-[6-(cyclopropylmethyl-methyl-a...)
Affinity DataIC50:  31.8nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol synthase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50130778((4-Bromo-phenyl)-{4-[6-(cyclopropyl-methyl-amino)-...)
Affinity DataIC50:  35.3nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed