Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50013972 Sort by
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataEC50:  5.30nMAssay Description:Ability to inhibit forskolin-stimulated adenylate cyclase activity in Chinese hamster ovary (CHO) stable cell lines expressing human 5-hydroxytryptam...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136469(4-[1-(2-Dimethylamino-ethyl)-1H-indol-6-yl]-tetrah...)
Affinity DataEC50:  0.300nMAssay Description:Ability to inhibit forskolin-stimulated adenylate cyclase activity in Chinese hamster ovary (CHO) stable cell lines expressing human 5-hydroxytryptam...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060429((R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136466(Dimethyl-[2-(6-pyridin-3-yl-indol-1-yl)-ethyl]-ami...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136469(4-[1-(2-Dimethylamino-ethyl)-1H-indol-6-yl]-tetrah...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136462(4-[1-(2-Dimethylamino-ethyl)-1H-indol-6-yl]-tetrah...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136465(Dimethyl-{2-[6-(tetrahydro-pyran-4-yl)-indol-1-yl]...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136471((S)-1-{2-[4-(4-Carbamoyl-phenyl)-piperazin-1-yl]-e...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136464(Dimethyl-{2-[6-(tetrahydro-thiopyran-4-yl)-indol-1...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136468(Dimethyl-[2-(6-thiophen-3-yl-indol-1-yl)-ethyl]-am...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136467({2-[6-(3,6-Dihydro-2H-thiopyran-4-yl)-indol-1-yl]-...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136463({2-[6-(3,6-Dihydro-2H-pyran-4-yl)-indol-1-yl]-ethy...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136470(Dimethyl-[2-(6-naphthalen-2-yl-indol-1-yl)-ethyl]-...)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed