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Found
41
Enz. Inhib. hit(s) with all data for entry = 5446
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ic50
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ki
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kcal/mole
Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Affinity Data
Ki: 0.560nM
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM28583
(CHEMBL431298 | SB 271046 | 5-chloro-N-[4-methoxy-3...)
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Affinity Data
Ki: 0.710nM
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50130286
(SB-258510 | CHEMBL29846 | 5-Chloro-3-methyl-benzo[...)
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Affinity Data
Ki: 0.760nM
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM28583
(CHEMBL431298 | SB 271046 | 5-chloro-N-[4-methoxy-3...)
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Affinity Data
Ki: 0.810nM
More data for this Ligand-Target Pair
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50130286
(SB-258510 | CHEMBL29846 | 5-Chloro-3-methyl-benzo[...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50130286
(SB-258510 | CHEMBL29846 | 5-Chloro-3-methyl-benzo[...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.02nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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Article
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Copy SMILES
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Affinity Data
Ki: 1.05nM
More data for this Ligand-Target Pair
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM28583
(CHEMBL431298 | SB 271046 | 5-chloro-N-[4-methoxy-3...)
Copy SMILES
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Affinity Data
Ki: 1.23nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50130268
(N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-(pipera...)
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Affinity Data
Ki: 1.41nM
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Copy SMILES
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Affinity Data
Ki: 1.41nM
More data for this Ligand-Target Pair
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM86428
(SB-258585)
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Affinity Data
Ki: 1.82nM
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM86427
(NSC_3981 | CAS_50-37-3 | LSD)
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Affinity Data
Ki: 2.29nM
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM86428
(SB-258585)
Copy SMILES
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Affinity Data
Ki: 2.29nM
More data for this Ligand-Target Pair
Target Info
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50130268
(N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-(pipera...)
Copy SMILES
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Affinity Data
Ki: 2.57nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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GoogleScholar
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CHEMBL
PC cid
PC sid
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM86427
(NSC_3981 | CAS_50-37-3 | LSD)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.63nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
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In Depth
Details
Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM86427
(NSC_3981 | CAS_50-37-3 | LSD)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.82nM
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
GoogleScholar
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PC sid
In Depth
Details
Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50073056
(CHEMBL292759 | SB-214111 | 4-Bromo-N-[4-methoxy-3-...)
Copy SMILES
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Affinity Data
Ki: 2.82nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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GoogleScholar
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CHEMBL
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PC sid
In Depth
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM31005
(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
Copy SMILES
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Affinity Data
Ki: 3.24nM
More data for this Ligand-Target Pair
Target Info
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PC cid
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In Depth
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50073056
(CHEMBL292759 | SB-214111 | 4-Bromo-N-[4-methoxy-3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.79nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
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PC sid
In Depth
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Copy SMILES
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Affinity Data
Ki: 6.46nM
More data for this Ligand-Target Pair
Target Info
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PC cid
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11.0nM
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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In Depth
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM86428
(SB-258585)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11.2nM
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
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PC cid
PC sid
In Depth
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14.4nM
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
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PC cid
PC sid
In Depth
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Copy SMILES
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Affinity Data
Ki: 22.4nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
PC sid
PDB
In Depth
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50073056
(CHEMBL292759 | SB-214111 | 4-Bromo-N-[4-methoxy-3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 22.9nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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GoogleScholar
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CHEMBL
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PC sid
In Depth
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Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 23.4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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GoogleScholar
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KEGG
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PDB
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50090528
(Ro-04-6790 | 4-Amino-N-(2,6-bis-dimethylamino-pyri...)
Copy SMILES
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Affinity Data
Ki: 28.8nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM31005
(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
Copy SMILES
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Affinity Data
Ki: 39.8nM
More data for this Ligand-Target Pair
Target Info
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50090528
(Ro-04-6790 | 4-Amino-N-(2,6-bis-dimethylamino-pyri...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 51.3nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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PC sid
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50130268
(N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-(pipera...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 61.7nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Copy SMILES
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Affinity Data
Ki: 69.2nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Copy SMILES
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Affinity Data
Ki: 79.4nM
More data for this Ligand-Target Pair
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM31005
(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 81.3nM
More data for this Ligand-Target Pair
Target Info
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In Depth
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
Copy SMILES
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Affinity Data
Ki: 89.1nM
More data for this Ligand-Target Pair
Target Info
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 95.5nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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CHEMBL
KEGG
PC cid
PC sid
In Depth
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Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 141nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
DrugBank
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 182nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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CHEMBL
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50005835
(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Copy SMILES
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Affinity Data
Ki: 5.62E+3nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Mouse)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50090528
(Ro-04-6790 | 4-Amino-N-(2,6-bis-dimethylamino-pyri...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
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CHEMBL
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Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 6
(Human)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50005835
(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
DrugBank
KEGG
PC cid
PC sid
In Depth
Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
5-hydroxytryptamine receptor 6
(Rat)
Glaxosmithkline
Curated by
PDSP K
i
Database
Ligand
BDBM50005835
(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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CHEMBL
DrugBank
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Details
Article
Copy BDB DOI
PubMed
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