Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50036021
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18771BDBM18771(CHEMBL389051 | (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dih...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against thymidylate synthase (TS) from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004387BDBM50004387(CHEMBL93048 | 2-{4-[(2,4-Dichloro-quinolin-6-ylmet...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004381BDBM50004381(CHEMBL545485 | 2-{4-[(2-Amino-4-chloro-quinolin-6-...)
Affinity DataIC50: 48nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004395BDBM50004395(CHEMBL92014 | 2-{4-[(2,4-Dichloro-quinolin-6-ylmet...)
Affinity DataIC50: 64nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004372BDBM50004372(2-{4-[(4-Chloro-2-methyl-quinolin-6-ylmethyl)-prop...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004376BDBM50004376(CHEMBL328173 | 2-{4-[(2-Amino-4-chloro-quinolin-6-...)
Affinity DataIC50: 96nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004373BDBM50004373(CHEMBL93037 | 2-{4-[(4-Bromo-2-methyl-quinolin-6-y...)
Affinity DataIC50: 96nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004383BDBM50004383(CHEMBL96355 | 2-{4-[(2-Chloro-4-methyl-quinolin-6-...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004396BDBM50004396(CHEMBL94195 | 2-{4-[(2-Chloro-4-methoxy-quinolin-6...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004392BDBM50004392(CHEMBL96911 | 2-{4-[(4-Chloro-2-trifluoromethyl-qu...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004394BDBM50004394(CHEMBL330103 | 2-{4-[(4-Bromo-2-methyl-quinolin-6-...)
Affinity DataIC50: 220nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004374BDBM50004374(CHEMBL92246 | 2-{4-[(4-Chloro-2-methyl-quinolin-6-...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004388BDBM50004388(CHEMBL92599 | 2-{4-[(2-Amino-4-methyl-quinolin-6-y...)
Affinity DataIC50: 350nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004368BDBM50004368(CHEMBL92341 | hydratemino]-benzoylamino}-pentanedi...)
Affinity DataIC50: 620nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004375BDBM50004375(CHEMBL96551 | 2-{4-[(4-Chloro-2-methyl-quinolin-6-...)
Affinity DataIC50: 740nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004380BDBM50004380(CHEMBL328247 | 2-{4-[(2,4-Dimethyl-quinolin-6-ylme...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004385BDBM50004385(CHEMBL411036 | 2-{4-[(4-Chloro-2-ethyl-quinolin-6-...)
Affinity DataIC50: 990nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004390BDBM50004390(CHEMBL329543 | 2-{4-[(4-Chloro-2-hydroxymethyl-qui...)
Affinity DataIC50: 1.05E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004393BDBM50004393(CHEMBL93098 | 2-{4-[(4-Chloro-quinolin-6-ylmethyl)...)
Affinity DataIC50: 1.13E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004366BDBM50004366(CHEMBL327692 | 2-{4-[(2-Acetylamino-4-chloro-quino...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004389BDBM50004389(CHEMBL96343 | 2-{4-[(4-Cyano-2-methyl-quinolin-6-y...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004384BDBM50004384(CHEMBL92445 | 2-{4-[(2-Amino-4-methoxy-quinolin-6-...)
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004377BDBM50004377(CHEMBL96656 | 2-{4-[(2-Carbamoyl-4-chloro-quinolin...)
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004369BDBM50004369(CHEMBL93086 | 2-{4-[(4-Chloro-2-methyl-quinolin-6-...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004386BDBM50004386(CHEMBL313846 | 2-{4-[(2-Chloro-quinolin-6-ylmethyl...)
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004391BDBM50004391(CHEMBL92944 | 2-{4-[(4-Methoxy-2-methyl-quinolin-6...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004365BDBM50004365(CHEMBL318292 | 2-{4-[(4-Hydroxy-2-methyl-quinolin-...)
Affinity DataIC50: 6.30E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004371BDBM50004371(CHEMBL432828 | 2-{4-[(2-Methyl-quinolin-6-ylmethyl...)
Affinity DataIC50: 7.90E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004378BDBM50004378(CHEMBL91743 | ; hydrate2-{4-[(2-Methyl-4-methylsul...)
Affinity DataIC50: 8.90E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004379BDBM50004379(CHEMBL328938 | 2-{4-[(4-Chloro-2-methoxy-quinolin-...)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004367BDBM50004367(CHEMBL431846 | 2-{4-[(2-Carboxy-4-chloro-quinolin-...)
Affinity DataIC50: 3.10E+4nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004382BDBM50004382(CHEMBL96086 | 2-{4-[(4-Chloro-2-methyl-quinolin-6-...)
Affinity DataIC50: 3.80E+4nMAssay Description:In vitro inhibitory activity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed