Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 2285
TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18867(2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.100nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18913(2-{3,5-dichloro-4-[3-(3-ethylphenyl)-4-hydroxyphen...)
Affinity DataIC50:  0.200nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataIC50:  0.240nMpH: 7.0 T: 4°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataIC50:  0.260nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18954(2-(3,5-dibromo-4-{3-[(2,2-diphenylethyl)carbamoyl]...)
Affinity DataIC50:  0.470nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18948(2-(3,5-dibromo-4-{4-hydroxy-3-[(2-phenylethyl)carb...)
Affinity DataIC50:  0.620nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18927(2-(3,5-dichloro-4-{3-[3-(difluoromethoxy)phenyl]-4...)
Affinity DataIC50:  0.770nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18922(2-(3,5-dichloro-4-{4-hydroxy-3-[3-(trifluoromethyl...)
Affinity DataIC50:  0.940nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50:  1.10nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18940(2-(3,5-dibromo-4-{4-hydroxy-3-[3-(trifluoromethyl)...)
Affinity DataIC50:  1.10nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18867(2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  1.40nMpH: 7.0 T: 4°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18920(2-[3,5-dichloro-4-(4-hydroxy-3-phenylphenoxy)pheny...)
Affinity DataIC50:  2.90nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18928(2-(3,5-dichloro-4-{4-hydroxy-3-[3-(trifluoromethox...)
Affinity DataIC50:  3.40nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18921(2-(3,5-dichloro-4-{4-hydroxy-3-[2-(trifluoromethyl...)
Affinity DataIC50:  3.40nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18956(2-(3,5-dichloro-4-{4-hydroxy-3-[(2-phenylethyl)car...)
Affinity DataIC50:  3.5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18924(2-(3,5-dichloro-4-{4-hydroxy-3-[3-(propan-2-yl)phe...)
Affinity DataIC50:  4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18947(2-{4-[3-(benzylcarbamoyl)-4-hydroxyphenoxy]-3,5-di...)
Affinity DataIC50:  4.20nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18952(2-[3,5-dibromo-4-(4-hydroxy-3-{[2-(3-methoxyphenyl...)
Affinity DataIC50:  4.80nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18938(2-[3,5-dibromo-4-(4-hydroxy-3-phenoxyphenoxy)pheny...)
Affinity DataIC50:  5.97nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18945(2-{3,5-dibromo-4-[4-hydroxy-3-(4-hydroxyphenoxy)ph...)
Affinity DataIC50:  6nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18949(2-(3,5-dibromo-4-{4-hydroxy-3-[(3-phenylpropyl)car...)
Affinity DataIC50:  6.80nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18939(2-(3,5-dibromo-4-{4-hydroxy-3-[2-(trifluoromethyl)...)
Affinity DataIC50:  7.63nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18937(2-[3,5-dichloro-4-(3-cyclohexyl-4-hydroxyphenoxy)p...)
Affinity DataIC50:  7.70nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18953(2-[3,5-dibromo-4-(4-hydroxy-3-{[2-(2-methoxyphenyl...)
Affinity DataIC50:  8.5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18941(2-(3,5-dibromo-4-{4-hydroxy-3-[4-(trifluoromethyl)...)
Affinity DataIC50:  9.5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18926(2-{3,5-dichloro-4-[4-hydroxy-3-(3-methoxyphenyl)ph...)
Affinity DataIC50:  11nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18913(2-{3,5-dichloro-4-[3-(3-ethylphenyl)-4-hydroxyphen...)
Affinity DataIC50:  13nMpH: 7.0 T: 4°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18948(2-(3,5-dibromo-4-{4-hydroxy-3-[(2-phenylethyl)carb...)
Affinity DataIC50:  15nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18950(2-(3,5-dibromo-4-{4-hydroxy-3-[(4-phenylbutyl)carb...)
Affinity DataIC50:  18nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18921(2-(3,5-dichloro-4-{4-hydroxy-3-[2-(trifluoromethyl...)
Affinity DataIC50:  18nMpH: 7.0 T: 4°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18954(2-(3,5-dibromo-4-{3-[(2,2-diphenylethyl)carbamoyl]...)
Affinity DataIC50:  18nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18925(2-{3,5-dichloro-4-[4-hydroxy-3-(3-phenylphenyl)phe...)
Affinity DataIC50:  21nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50:  25nMpH: 7.0 T: 4°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18936(2-{3,5-dichloro-4-[4-hydroxy-3-(1,3-thiazol-2-yl)p...)
Affinity DataIC50:  28nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18927(2-(3,5-dichloro-4-{3-[3-(difluoromethoxy)phenyl]-4...)
Affinity DataIC50:  30nMpH: 7.0 T: 4°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18946(2-{3,5-dibromo-4-[4-hydroxy-3-(phenylcarbamoyl)phe...)
Affinity DataIC50:  35nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18951(2-[3,5-dibromo-4-(4-hydroxy-3-{[2-(4-methoxyphenyl...)
Affinity DataIC50:  37nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18922(2-(3,5-dichloro-4-{4-hydroxy-3-[3-(trifluoromethyl...)
Affinity DataIC50:  40nMpH: 7.0 T: 4°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18933(2-{3,5-dichloro-4-[4-hydroxy-3-(pyridin-3-yl)pheno...)
Affinity DataIC50:  41nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18944(2-{3,5-dibromo-4-[4-hydroxy-3-(3-hydroxyphenoxy)ph...)
Affinity DataIC50:  47nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18929(2-{3,5-dichloro-4-[4-hydroxy-3-(2-hydroxyphenyl)ph...)
Affinity DataIC50:  50nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18940(2-(3,5-dibromo-4-{4-hydroxy-3-[3-(trifluoromethyl)...)
Affinity DataIC50:  50nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18942(2-{3,5-dibromo-4-[4-hydroxy-3-(3-phenylphenoxy)phe...)
Affinity DataIC50:  60nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18935(2-{3,5-dichloro-4-[4-hydroxy-3-(pyrimidin-5-yl)phe...)
Affinity DataIC50:  67nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18923(2-(3,5-dichloro-4-{4-hydroxy-3-[4-(trifluoromethyl...)
Affinity DataIC50:  67nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18955(2-[3,5-dibromo-4-(4-hydroxy-3-{[2-(pyridin-2-yl)et...)
Affinity DataIC50:  67nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18930(2-{3,5-dichloro-4-[4-hydroxy-3-(3-hydroxyphenyl)ph...)
Affinity DataIC50:  75nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18943(2-{3,5-dibromo-4-[4-hydroxy-3-(2-hydroxyphenoxy)ph...)
Affinity DataIC50:  83nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18947(2-{4-[3-(benzylcarbamoyl)-4-hydroxyphenoxy]-3,5-di...)
Affinity DataIC50:  84nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18931(2-{3,5-dichloro-4-[4-hydroxy-3-(4-hydroxyphenyl)ph...)
Affinity DataIC50:  87nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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