Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50014971
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076091BDBM50076091((3S,3aR,4R,4aS,8aR,9aS)-4-[2-((2R,6S)-1,6-Dimethyl...)
Affinity DataKi:  4.30nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076089BDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-4-[(E)-2-((1S,2R,6S)-1,6-D...)
Affinity DataKi:  4.5nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149715BDBM50149715((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  12.2nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149716BDBM50149716((3S,3aS,4aS,8aR,9aS)-4-[2-((2R,6S)-1,6-Dimethyl-pi...)
Affinity DataKi:  13.3nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149713BDBM50149713((3S,3aR,4R,4aS,8aR,9aS)-4-[(E)-2-((2R,6S)-1,6-Dime...)
Affinity DataKi:  16nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076091BDBM50076091((3S,3aR,4R,4aS,8aR,9aS)-4-[2-((2R,6S)-1,6-Dimethyl...)
Affinity DataKi:  32nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149726BDBM50149726((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  43nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076089BDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-4-[(E)-2-((1S,2R,6S)-1,6-D...)
Affinity DataKi:  48nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149716BDBM50149716((3S,3aS,4aS,8aR,9aS)-4-[2-((2R,6S)-1,6-Dimethyl-pi...)
Affinity DataKi:  65.9nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149725BDBM50149725((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  68nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149713BDBM50149713((3S,3aR,4R,4aS,8aR,9aS)-4-[(E)-2-((2R,6S)-1,6-Dime...)
Affinity DataKi:  68nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149715BDBM50149715((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  122nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149725BDBM50149725((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  177nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149724BDBM50149724((S)-6,6,7-Trimethyl-2-((3S,3aR,4R,4aR,9aS)-3-methy...)
Affinity DataKi:  180nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149723BDBM50149723((1S,4aR,5S,9aS)-4-[2-((2R,6S)-1,6-Dimethyl-piperid...)
Affinity DataKi:  203nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149726BDBM50149726((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  418nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149717BDBM50149717((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  446nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149722BDBM50149722((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  449nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149717BDBM50149717((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  571nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149719BDBM50149719((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  640nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149724BDBM50149724((S)-6,6,7-Trimethyl-2-((3S,3aR,4R,4aR,9aS)-3-methy...)
Affinity DataKi:  790nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149722BDBM50149722((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi:  811nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149721BDBM50149721((3S,3aR,4R,4aR,9aS)-4-((S)-6,6-Dimethyl-hexahydro-...)
Affinity DataKi: >1.40E+3nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149721BDBM50149721((3S,3aR,4R,4aR,9aS)-4-((S)-6,6-Dimethyl-hexahydro-...)
Affinity DataKi: >1.40E+3nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149718BDBM50149718((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[(E)-2-((2S,6S)...)
Affinity DataKi: >1.40E+3nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149720BDBM50149720((3S,3aR,4R,4aS,8aR,9aS)-4-[(E)-2-((2S,6S)-1,6-Dime...)
Affinity DataKi: >1.40E+3nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149720BDBM50149720((3S,3aR,4R,4aS,8aR,9aS)-4-[(E)-2-((2S,6S)-1,6-Dime...)
Affinity DataKi: >1.40E+3nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149719BDBM50149719((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-(1,5,5-...)
Affinity DataKi: >1.40E+3nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149718BDBM50149718((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[(E)-2-((2S,6S)...)
Affinity DataKi: >1.40E+3nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149714BDBM50149714((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-((R)-1,...)
Affinity DataKi: >1.40E+3nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149714BDBM50149714((3S,3aR,4R,4aS,8aR,9aS)-4-[(S)-1-Hydroxy-2-((R)-1,...)
Affinity DataKi: >1.40E+3nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149723BDBM50149723((1S,4aR,5S,9aS)-4-[2-((2R,6S)-1,6-Dimethyl-piperid...)
Affinity DataKi:  1.57E+3nMAssay Description:In vitro inhibitory activity against cloned human M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed