Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50015031
TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150528BDBM50150528((S)-4-Methyl-2-[4-(4-piperazin-1-yl-phenyl)-thioph...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration against human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150528BDBM50150528((S)-4-Methyl-2-[4-(4-piperazin-1-yl-phenyl)-thioph...)
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150525BDBM50150525(4-Methyl-2-(4''-piperazin-1-yl-biphenyl-3-ylamino)...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150524BDBM50150524((S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-2-ylam...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19856BDBM19856((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(piperazin-1...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19856BDBM19856((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(piperazin-1...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150525BDBM50150525(4-Methyl-2-(4''-piperazin-1-yl-biphenyl-3-ylamino)...)
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration against human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150532BDBM50150532((S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-4-ylam...)
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150532BDBM50150532((S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-4-ylam...)
Affinity DataIC50: 27nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150532BDBM50150532((S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-4-ylam...)
Affinity DataIC50: 34nMAssay Description:Inhibitory concentration against human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150527BDBM50150527(2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150536BDBM50150536(2-(2-Bromo-phenylamino)-4-methyl-pentanoic acid cy...)
Affinity DataIC50: 54nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150526BDBM50150526(2-(3-Bromo-phenylamino)-4-methyl-pentanoic acid cy...)
Affinity DataIC50: 72nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150525BDBM50150525(4-Methyl-2-(4''-piperazin-1-yl-biphenyl-3-ylamino)...)
Affinity DataIC50: 93nMAssay Description:Inhibitory concentration against human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150528BDBM50150528((S)-4-Methyl-2-[4-(4-piperazin-1-yl-phenyl)-thioph...)
Affinity DataIC50: 102nMAssay Description:Inhibitory concentration against human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150525BDBM50150525(4-Methyl-2-(4''-piperazin-1-yl-biphenyl-3-ylamino)...)
Affinity DataIC50: 108nMAssay Description:Inhibitory concentration against human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150532BDBM50150532((S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-4-ylam...)
Affinity DataIC50: 115nMAssay Description:Inhibitory concentration against human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150528BDBM50150528((S)-4-Methyl-2-[4-(4-piperazin-1-yl-phenyl)-thioph...)
Affinity DataIC50: 123nMAssay Description:Inhibitory concentration against human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150524BDBM50150524((S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-2-ylam...)
Affinity DataIC50: 158nMAssay Description:Inhibitory concentration against human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150527BDBM50150527(2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 158nMAssay Description:Inhibitory concentration against human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150529BDBM50150529(2-(4-Bromo-phenylamino)-4-methyl-pentanoic acid cy...)
Affinity DataIC50: 208nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150528BDBM50150528((S)-4-Methyl-2-[4-(4-piperazin-1-yl-phenyl)-thioph...)
Affinity DataIC50: 352nMAssay Description:Inhibitory concentration against human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150535BDBM50150535(2-(2-Bromo-phenylsulfanyl)-4-methyl-pentanoic acid...)
Affinity DataIC50: 433nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150527BDBM50150527(2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 458nMAssay Description:Inhibitory concentration against human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150533BDBM50150533(2-(4-Bromo-phenylsulfanyl)-4-methyl-pentanoic acid...)
Affinity DataIC50: 675nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150534BDBM50150534(2-(3-Bromo-phenylsulfanyl)-4-methyl-pentanoic acid...)
Affinity DataIC50: 684nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150527BDBM50150527(2-(4-Bromo-thiophen-3-ylamino)-4-methyl-pentanoic ...)
Affinity DataIC50: 897nMAssay Description:Inhibitory concentration against human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150531BDBM50150531(2-(2-Bromo-phenoxy)-4-methyl-pentanoic acid cyanom...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150523BDBM50150523(2-(3-Bromo-phenoxy)-4-methyl-pentanoic acid cyanom...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150524BDBM50150524((S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-2-ylam...)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibitory concentration against human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19856BDBM19856((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(piperazin-1...)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibitory concentration against human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150524BDBM50150524((S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-2-ylam...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration against human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150539BDBM50150539(2-(2-Bromo-benzyl)-4-methyl-pentanoic acid cyanome...)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150537BDBM50150537(2-(4-Bromo-benzyl)-4-methyl-pentanoic acid cyanome...)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150530BDBM50150530(2-(4-Bromo-phenoxy)-4-methyl-pentanoic acid cyanom...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150538BDBM50150538(2-(3-Bromo-benzyl)-4-methyl-pentanoic acid cyanome...)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibitory concentration against humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19856BDBM19856((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(piperazin-1...)
Affinity DataIC50: 3.73E+3nMAssay Description:Inhibitory concentration against human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19856BDBM19856((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(piperazin-1...)
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibitory concentration against human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed