Compile Data Set for Download or QSAR
maximum 50k data
Found 58 Enz. Inhib. hit(s) with all data for entry = 50015620
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158453(CHEMBL224400 | N-(3-Phenylamino-4-pyridinyl)triflu...)
Affinity DataIC50:  90nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158450(CHEMBL224136 | N-[3-(2,4-dichlorophenoxy)-4-pyridi...)
Affinity DataIC50:  120nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158444(CHEMBL388628 | N-(3-(2-chlorophenoxy)-4-pyridinyl)...)
Affinity DataIC50:  130nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50120981(1,1,1-trifluoro-N-(3-phenoxypyridin-4-yl)methanesu...)
Affinity DataIC50:  140nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158451(CHEMBL224640 | N-[3-(2-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  150nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158453(CHEMBL224400 | N-(3-Phenylamino-4-pyridinyl)triflu...)
Affinity DataIC50:  180nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158443(CHEMBL374168 | N-[3-(4-bromophenoxy)-4-pyridinyl]t...)
Affinity DataIC50:  240nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158438(CHEMBL225092 | N-[3-(4-methoxyphenoxy)-4-pyridinyl...)
Affinity DataIC50:  260nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158451(CHEMBL224640 | N-[3-(2-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  270nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  350nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158432(CHEMBL225113 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  360nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50120980(CHEMBL148542 | N-(3-Phenoxy-pyridin-4-yl)-methanes...)
Affinity DataIC50:  410nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158437(CHEMBL224612 | N-(3-phenylsulfanyl-4-pyridinyl)tri...)
Affinity DataIC50:  410nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158438(CHEMBL225092 | N-[3-(4-methoxyphenoxy)-4-pyridinyl...)
Affinity DataIC50:  440nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158437(CHEMBL224612 | N-(3-phenylsulfanyl-4-pyridinyl)tri...)
Affinity DataIC50:  530nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50120981(1,1,1-trifluoro-N-(3-phenoxypyridin-4-yl)methanesu...)
Affinity DataIC50:  620nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158450(CHEMBL224136 | N-[3-(2,4-dichlorophenoxy)-4-pyridi...)
Affinity DataIC50:  620nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50056999(CHEMBL56367 | nimesulide)
Affinity DataIC50:  700nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158444(CHEMBL388628 | N-(3-(2-chlorophenoxy)-4-pyridinyl)...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158452(CHEMBL224122 | N-(3-(phenylthio)pyridin-4-yl)metha...)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158440(CHEMBL387879 | N-[3-(2,4-dichlorophenoxy)-4-pyridi...)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158442(CHEMBL224193 | N-[3-(4-bromophenoxy)-4-pyridinyl]m...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158456(CHEMBL388625 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158432(CHEMBL225113 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158436(CHEMBL224624 | N-[3-(4-methoxyphenoxy)-4-pyridinyl...)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158456(CHEMBL388625 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158435(CHEMBL224192 | N-[3-(3-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  1.99E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158441(CHEMBL224693 | N-[3-(3-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158447(CHEMBL374169 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158436(CHEMBL224624 | N-[3-(4-methoxyphenoxy)-4-pyridinyl...)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158439(CHEMBL223655 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158440(CHEMBL387879 | N-[3-(2,4-dichlorophenoxy)-4-pyridi...)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158439(CHEMBL223655 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158452(CHEMBL224122 | N-(3-(phenylthio)pyridin-4-yl)metha...)
Affinity DataIC50:  3.62E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50056999(CHEMBL56367 | nimesulide)
Affinity DataIC50:  3.76E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158433(CHEMBL224401 | N-[3-(N'-methyl-N'-phenylamino)-4-p...)
Affinity DataIC50:  4.63E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158446(CHEMBL376143 | N-(3-phenoxy-4-pyridinyl)ethanesulf...)
Affinity DataIC50:  5.34E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158442(CHEMBL224193 | N-[3-(4-bromophenoxy)-4-pyridinyl]m...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158447(CHEMBL374169 | N-[3-(4-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  9.69E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158435(CHEMBL224192 | N-[3-(3-chlorophenoxy)-4-pyridinyl]...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158443(CHEMBL374168 | N-[3-(4-bromophenoxy)-4-pyridinyl]t...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158446(CHEMBL376143 | N-(3-phenoxy-4-pyridinyl)ethanesulf...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158449(CHEMBL389485 | N-(3-phenoxy-4-pyridinyl)propanesul...)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158445(CHEMBL224781 | N-(3-phenylsulfinyl-4-pyridinyl)tri...)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158433(CHEMBL224401 | N-[3-(N'-methyl-N'-phenylamino)-4-p...)
Affinity DataIC50:  4.76E+4nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158434(CHEMBL224256 | N-(3-phenylsulfonyl-4-pyridinyl)met...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158455(CHEMBL390317 | N-[3-(3,5-dichlorophenoxy)-4-pyridi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158454(CHEMBL225236 | N-[3-(3,5-dichlorophenoxy)-4-pyridi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158445(CHEMBL224781 | N-(3-phenylsulfinyl-4-pyridinyl)tri...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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