Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 2705
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23585BDBM23585(2-{[4-(4-methanesulfonylphenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23587BDBM23587(2-hydroxy-6-[(3-phenoxy-4-phenylbenzene)amido]benz...)
Affinity DataIC50: 4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23587BDBM23587(2-hydroxy-6-[(3-phenoxy-4-phenylbenzene)amido]benz...)
Affinity DataIC50: 4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23585BDBM23585(2-{[4-(4-methanesulfonylphenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 28nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23586BDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 34nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23584BDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23584BDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 56nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23586BDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 62nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23595BDBM23595(2-({3-phenoxy-4-[4-(trifluoromethyl)phenyl]benzene...)
Affinity DataIC50: 96nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23594BDBM23594(2-{[3-phenoxy-4-(pyridin-3-yl)benzene]amido}benzoi...)
Affinity DataIC50: 110nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23606BDBM23606(2-{[4-(2,4-difluorophenyl)-3-phenoxybenzene]amido}...)
Affinity DataIC50: 160nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23596BDBM23596(2-{[4-(4-methylphenyl)-3-phenoxybenzene]amido}benz...)
Affinity DataIC50: 160nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23599BDBM23599(2-{[4-(4-ethoxyphenyl)-3-phenoxybenzene]amido}benz...)
Affinity DataIC50: 220nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23602BDBM23602(2-{[4-(4-fluoro-3-methylphenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 240nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23605BDBM23605(2-{[4-(4-chloro-3-methylphenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 250nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23592BDBM23592(2-{[4-(3,5-dimethylpiperidin-1-yl)-3-phenoxybenzen...)
Affinity DataIC50: 270nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23591BDBM23591(2-{[3-phenoxy-4-(piperidin-1-yl)benzene]amido}benz...)
Affinity DataIC50: 290nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23604BDBM23604(2-{[4-(3,4-difluorophenyl)-3-phenoxybenzene]amido}...)
Affinity DataIC50: 330nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23612BDBM23612(2-hydroxy-6-[(3-phenoxybenzene)amido]benzoic acid ...)
Affinity DataIC50: 410nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23598BDBM23598(2-{[4-(4-hydroxyphenyl)-3-phenoxybenzene]amido}ben...)
Affinity DataIC50: 410nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23601BDBM23601(2-({3-phenoxy-4-[3-(trifluoromethoxy)phenyl]benzen...)
Affinity DataIC50: 470nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23603BDBM23603(2-{[4-(3-chloro-4-fluorophenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 570nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23600BDBM23600(2-({3-phenoxy-4-[3-(propan-2-yl)phenyl]benzene}ami...)
Affinity DataIC50: 790nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23581BDBM23581(2-[(4-bromo-3-phenoxybenzene)amido]benzoic acid | ...)
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23590BDBM23590(2-{[3-phenoxy-4-(thiomorpholin-4-yl)benzene]amido}...)
Affinity DataIC50: 1.20E+3nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23570BDBM23570(2-{[4-bromo-3-(diethylsulfamoyl)benzene]amido}benz...)
Affinity DataIC50: 1.60E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23572BDBM23572(2-{[3-(diethylsulfamoyl)-4-phenylbenzene]amido}ben...)
Affinity DataIC50: 1.60E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23597BDBM23597(4-{4-[(2-carboxyphenyl)carbamoyl]-2-phenoxyphenyl}...)
Affinity DataIC50: 2.10E+3nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23578BDBM23578(2-{[4-(cyclopentylmethoxy)-3-(diethylsulfamoyl)ben...)
Affinity DataIC50: 2.10E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23576BDBM23576(2-{[3-(diethylsulfamoyl)-4-(piperidin-1-yl)benzene...)
Affinity DataIC50: 2.20E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23587BDBM23587(2-hydroxy-6-[(3-phenoxy-4-phenylbenzene)amido]benz...)
Affinity DataIC50: 2.40E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23579BDBM23579(2-[(3-phenoxybenzene)amido]benzoic acid | (3-Pheno...)
Affinity DataIC50: 2.70E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23589BDBM23589(2-{[4-(morpholin-4-yl)-3-phenoxybenzene]amido}benz...)
Affinity DataIC50: 3.20E+3nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23614BDBM23614(3-{3-[(2-carboxyphenyl)carbamoyl]phenoxy}benzoic a...)
Affinity DataIC50: 3.70E+3nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23587BDBM23587(2-hydroxy-6-[(3-phenoxy-4-phenylbenzene)amido]benz...)
Affinity DataIC50: 3.80E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23580BDBM23580(2-[(4-fluoro-3-phenoxybenzene)amido]benzoic acid |...)
Affinity DataIC50: 3.80E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23615BDBM23615(4-{3-[(2-carboxyphenyl)carbamoyl]phenoxy}benzoic a...)
Affinity DataIC50: 4.40E+3nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23616BDBM23616(2-{[3-(4-fluorophenoxy)benzene]amido}benzoic acid ...)
Affinity DataIC50: 5.00E+3nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23611BDBM23611(2-fluoro-6-[(3-phenoxybenzene)amido]benzoic acid |...)
Affinity DataIC50: 6.00E+3nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23577BDBM23577(2-{[3-(diethylsulfamoyl)-4-phenoxybenzene]amido}be...)
Affinity DataIC50: 6.10E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23575BDBM23575(2-{[3-(diethylsulfamoyl)-4-fluorobenzene]amido}ben...)
Affinity DataIC50: 8.40E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23584BDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23613BDBM23613(2-{[3-(pyridin-4-yloxy)benzene]amido}benzoic acid ...)
Affinity DataIC50: 1.00E+4nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23607BDBM23607(3-[(3-phenoxybenzene)amido]thiophene-2-carboxylic ...)
Affinity DataIC50: 1.01E+4nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23574BDBM23574(2-{[3-(diethylsulfamoyl)-4-methoxybenzene]amido}be...)
Affinity DataIC50: 1.14E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23586BDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 1.23E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23586BDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 2.00E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23593BDBM23593(2-{[3-phenoxy-4-(1H-pyrazol-4-yl)benzene]amido}ben...)
Affinity DataIC50: 2.20E+4nMAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23585BDBM23585(2-{[4-(4-methanesulfonylphenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 2.40E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 23583BDBM23583(2-{[4-(4-methylpiperazin-1-yl)-3-phenoxybenzene]am...)
Affinity DataIC50: 2.50E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
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