Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50037566
TargetDNA topoisomerase 1(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50073854(2,10-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of topoisomerase I-DNA complex in trapping assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50008935(CHEMBL84 | 10-Dimethylaminomethyl-4-ethyl-4,9-dihy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of topoisomerase I-DNA complex in trapping assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 300nMAssay Description:Inhibition of topoisomerase I-DNA complex in trapping assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50164286(4-(5,11-Dioxo-5,6a,11,11a-tetrahydro-indeno[1,2-c]...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of topoisomerase I-DNA complex in trapping assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed