Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50016490
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169627BDBM50169627(7-Cyclopentyl-2-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 1nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169633BDBM50169633(7-Cyclopentyl-2-[2-ethoxy-5-(4-methyl-piperazine-1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169652BDBM50169652(6-(2-Ethoxy-phenyl)-3-methyl-1-propyl-1,5-dihydro-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111902BDBM50111902(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 2nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169635BDBM50169635(7-Cyclopentyl-2-(2-ethoxy-phenyl)-5-methyl-3H-imid...)
Affinity DataIC50: 5nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169634BDBM50169634(3-Cyclopentyl-5-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 5nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169641BDBM50169641(2-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50: 5nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111897BDBM50111897(2-(2-Ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5...)
Affinity DataIC50: 5nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14390BDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169647BDBM50169647(7-Cyclopentyl-2-[2-ethoxy-5-(4-methyl-piperazine-1...)
Affinity DataIC50: 7nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169639BDBM50169639(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 8nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169630BDBM50169630(6-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 8nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169626BDBM50169626(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169627BDBM50169627(7-Cyclopentyl-2-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 10nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50024352BDBM50024352(CHEMBL183857)
Affinity DataIC50: 10nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169625BDBM50169625(2-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50: 10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169637BDBM50169637(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169648BDBM50169648(3-Cyclopentyl-5-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169643BDBM50169643(8-Cyclopentyl-2-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169634BDBM50169634(3-Cyclopentyl-5-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 10nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169633BDBM50169633(7-Cyclopentyl-2-[2-ethoxy-5-(4-methyl-piperazine-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169641BDBM50169641(2-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50: 20nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169631BDBM50169631(3-Cyclopentyl-5-(2-ethoxy-phenyl)-6H-isoxazolo[4,5...)
Affinity DataIC50: 20nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169651BDBM50169651(8-Cyclopentyl-2-(2-ethoxy-phenyl)-6-methyl-3H-imid...)
Affinity DataIC50: 20nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169646BDBM50169646(6-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 20nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111899BDBM50111899(5-(2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4...)
Affinity DataIC50: 27nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169635BDBM50169635(7-Cyclopentyl-2-(2-ethoxy-phenyl)-5-methyl-3H-imid...)
Affinity DataIC50: 30nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169643BDBM50169643(8-Cyclopentyl-2-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 30nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169648BDBM50169648(3-Cyclopentyl-5-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 30nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169624BDBM50169624(1-Cyclopentyl-6-[2-ethoxy-5-(4-methyl-piperazine-1...)
Affinity DataIC50: 40nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169645BDBM50169645(2-(2-Ethoxy-phenyl)-6-methyl-8-propyl-3H-imidazo[1...)
Affinity DataIC50: 40nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169651BDBM50169651(8-Cyclopentyl-2-(2-ethoxy-phenyl)-6-methyl-3H-imid...)
Affinity DataIC50: 40nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169632BDBM50169632(3-Cyclopentyl-6-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 50nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169628BDBM50169628(9-Cyclopentyl-2-(2-ethoxy-phenyl)-1,9-dihydro-puri...)
Affinity DataIC50: 50nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169640BDBM50169640(5-(2-Ethoxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo[...)
Affinity DataIC50: 50nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169632BDBM50169632(3-Cyclopentyl-6-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50: 50nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169636BDBM50169636(3-Cyclopentyl-6-(2-ethoxy-phenyl)-7H-[1,2,4]triazo...)
Affinity DataIC50: 50nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169629BDBM50169629(9-Cyclobutyl-2-(2-ethoxy-phenyl)-1,9-dihydro-purin...)
Affinity DataIC50: 100nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169631BDBM50169631(3-Cyclopentyl-5-(2-ethoxy-phenyl)-6H-isoxazolo[4,5...)
Affinity DataIC50: 200nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169649BDBM50169649(2-(2-Ethoxy-phenyl)-5,7-dimethyl-3H-imidazo[5,1-f]...)
Affinity DataIC50: 200nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169636BDBM50169636(3-Cyclopentyl-6-(2-ethoxy-phenyl)-7H-[1,2,4]triazo...)
Affinity DataIC50: 200nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169645BDBM50169645(2-(2-Ethoxy-phenyl)-6-methyl-8-propyl-3H-imidazo[1...)
Affinity DataIC50: 200nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169642BDBM50169642(9-Cyclopropyl-2-(2-ethoxy-phenyl)-1,9-dihydro-puri...)
Affinity DataIC50: 300nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169638BDBM50169638(5-(2-Ethoxy-phenyl)-3-propyl-3,6-dihydro-[1,2,3]tr...)
Affinity DataIC50: 300nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50111897BDBM50111897(2-(2-Ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5...)
Affinity DataIC50: 300nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50111902BDBM50111902(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 300nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14390BDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 400nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169628BDBM50169628(9-Cyclopentyl-2-(2-ethoxy-phenyl)-1,9-dihydro-puri...)
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169644BDBM50169644(3-Cyclopentyl-5-(2-ethoxy-phenyl)-3,6-dihydro-[1,2...)
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50169637BDBM50169637(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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