Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50037409
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170193BDBM50170193(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170189BDBM50170189(4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamin...)
Affinity DataIC50: 2.70nMAssay Description:Inhibitory activity against neuropeptide Y receptor type 5 by using [125I]PYY as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170191BDBM50170191(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170180BDBM50170180(3-Chloro-N-[4-(4-dimethylamino-quinazolin-2-ylamin...)
Affinity DataIC50: 4.5nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170179BDBM50170179(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170192BDBM50170192(cis-N*2*-{4-[(4-Bromo-2-trifluoromethoxy-benzylami...)
Affinity DataIC50: 4.90nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170182BDBM50170182(3,4-Dichloro-N-[4-(4-dimethylamino-quinazolin-2-yl...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170176BDBM50170176(3-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Affinity DataIC50: 5.90nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170200BDBM50170200(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 6.80nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170189BDBM50170189(4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamin...)
Affinity DataIC50: 7.70nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170199BDBM50170199(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 9.40nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170198BDBM50170198(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 9.5nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170194BDBM50170194(trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-...)
Affinity DataIC50: 9.90nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170195BDBM50170195(3-Cyano-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170183BDBM50170183(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170177BDBM50170177(trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-...)
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170187BDBM50170187(trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-...)
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170175BDBM50170175(cis-N*2*-[4-(4-Bromo-2-trifluoromethoxy-benzylamin...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170185BDBM50170185(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170196BDBM50170196(trans-N*2*-(4-{[(4-Bromo-2-trifluoromethoxy-benzyl...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170182BDBM50170182(3,4-Dichloro-N-[4-(4-dimethylamino-quinazolin-2-yl...)
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170184BDBM50170184(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Affinity DataIC50: 57nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170183BDBM50170183(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170176BDBM50170176(3-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170193BDBM50170193(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 71nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170180BDBM50170180(3-Chloro-N-[4-(4-dimethylamino-quinazolin-2-ylamin...)
Affinity DataIC50: 76nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170181BDBM50170181(cis-4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-yla...)
Affinity DataIC50: 79nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170184BDBM50170184(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Affinity DataIC50: 83nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170200BDBM50170200(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 97nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170179BDBM50170179(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170178BDBM50170178(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against neuropeptide Y receptor type 5 by using [125I]PYY as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170198BDBM50170198(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170178BDBM50170178(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170178BDBM50170178(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170199BDBM50170199(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170195BDBM50170195(3-Cyano-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170189BDBM50170189(4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamin...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170190BDBM50170190(cis-4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-yla...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170197BDBM50170197(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170175BDBM50170175(cis-N*2*-[4-(4-Bromo-2-trifluoromethoxy-benzylamin...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166556BDBM50166556(N*2*-[1-(4-Bromo-2-trifluoromethoxy-benzenesulfony...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170185BDBM50170185(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166556BDBM50166556(N*2*-[1-(4-Bromo-2-trifluoromethoxy-benzenesulfony...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170191BDBM50170191(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170186BDBM50170186(N*2*-[1-(4-Bromo-2-trifluoromethoxy-benzyl)-piperi...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170192BDBM50170192(cis-N*2*-{4-[(4-Bromo-2-trifluoromethoxy-benzylami...)
Affinity DataIC50: 360nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170190BDBM50170190(cis-4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-yla...)
Affinity DataIC50: 390nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170187BDBM50170187(trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-...)
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against neuropeptide Y receptor type 5 by using [125I]PYY as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170194BDBM50170194(trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-...)
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against neuropeptide Y receptor type 5 by using [125I]PYY as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170186BDBM50170186(N*2*-[1-(4-Bromo-2-trifluoromethoxy-benzyl)-piperi...)
Affinity DataIC50: 520nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
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