Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50017283
Target5-hydroxytryptamine receptor 1A(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 8.5nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 9.10nMAssay Description:Binding affinity to human 5HT7 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Binding affinity to adrenergic alpha-2C receptorMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Binding affinity to adrenergic alpha-1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Binding affinity to adrenergic beta-2 receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Binding affinity to human 5HT6 receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 229nMAssay Description:Binding affinity to human 5HT5A receptorMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 302nMAssay Description:Binding affinity to histamine H2 receptorMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 316nMAssay Description:Binding affinity to adrenergic alpha-2B receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 407nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 476nMAssay Description:Binding affinity to adrenergic beta-1 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Binding affinity to sigma1 receptorMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 1.01E+3nMAssay Description:Binding affinity to adrenergic alpha-2A receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 6.14E+3nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 6.98E+3nMAssay Description:Binding affinity to NETMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: 7.40E+3nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to histamine H4 receptorMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to vasopressin 2 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to adenosine A4 receptorMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to MDR1More data for this Ligand-Target Pair
TargetChromaffin granule amine transporter(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to VMAT1More data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to adenosine A3 receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
TargetTumor necrosis factor receptor superfamily member 16(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to neurotrophin receptorMore data for this Ligand-Target Pair
TargetSynaptic vesicular amine transporter(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to VMAT2More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to hERGMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to histamine H3 receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to adenosine A2 receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to Delta opioid receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to muscarinic receptorMore data for this Ligand-Target Pair
TargetVasopressin V1a/V1b receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to vasopressin 1 receptorMore data for this Ligand-Target Pair
TargetBeta-3 adrenergic receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to adrenergic beta-3 receptorMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine D5 receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonistic activity at human 5HT1A in CHO cells by the inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
3D Structure (crystal)Target5-hydroxytryptamine receptor 1A(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 0.0100nMAssay Description:Agonistic activity at human 5HT1A in CHO cells by the inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 0.0500nMAssay Description:Agonistic activity at human 5HT1A receptor by [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonistic activity at human 5HT1A in CHO cells by the inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
