Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50017639
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184857(CHEMBL203227 | N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184863(CHEMBL202919 | N-(2-Chlorobenzoyl)-N'-{4-[(6,7-dim...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184860(CHEMBL380703 | Phenyl N-{4-[(6,7-Dimethoxy-4-quino...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184858(CHEMBL425935 | N-(2-Cyclohexyl)ethyl-N'-{4-[(6,7-d...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184864(CHEMBL203279 | N-{4-[(6,7-Dimethoxy-4-quinazolinyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184861(CHEMBL205089 | N-Cyclohexyl-N'-{4-[6,7-dimethoxy-4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184857(CHEMBL203227 | N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cell by transactivation enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184868(CHEMBL378489 | N-Benzoyl-N'-{4-[(6,7-dimethoxy-4-q...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184856(CHEMBL204225 | N-(2-Cyclohexyl)ethyl-N'-{4-[(6,7-d...)
Affinity DataIC50:  9nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184870(CHEMBL205953 | N-Cyclohexyl-N'-{4-[6,7-dimethoxy-4...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184859(CHEMBL204120 | N-Cyclohexylcarbonyl-N'-{4-[(6,7-di...)
Affinity DataIC50:  15nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184867(2-Cyclohexylethyl N-{4-[(6,7-Dimethoxy-4-quinolyl)...)
Affinity DataIC50:  18nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184860(CHEMBL380703 | Phenyl N-{4-[(6,7-Dimethoxy-4-quino...)
Affinity DataIC50:  19nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184870(CHEMBL205953 | N-Cyclohexyl-N'-{4-[6,7-dimethoxy-4...)
Affinity DataIC50:  22nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184861(CHEMBL205089 | N-Cyclohexyl-N'-{4-[6,7-dimethoxy-4...)
Affinity DataIC50:  27nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184869(1-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-3-(2-p...)
Affinity DataIC50:  28nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184866(CHEMBL382399 | N-Cyclohexylmethyl-N'-{4-[(6,7-dime...)
Affinity DataIC50:  37nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184865(1-cyclohexyl-3-(4-(6,7-dimethoxyquinolin-4-yloxy)p...)
Affinity DataIC50:  40nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184862(CHEMBL204409 | N-Benzyl-N'-{4-[(6,7-dimethoxy-4-qu...)
Affinity DataIC50:  46nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184865(1-cyclohexyl-3-(4-(6,7-dimethoxyquinolin-4-yloxy)p...)
Affinity DataIC50:  69nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184867(2-Cyclohexylethyl N-{4-[(6,7-Dimethoxy-4-quinolyl)...)
Affinity DataIC50:  80nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  96nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184866(CHEMBL382399 | N-Cyclohexylmethyl-N'-{4-[(6,7-dime...)
Affinity DataIC50:  153nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184869(1-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-3-(2-p...)
Affinity DataIC50:  202nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  219nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184859(CHEMBL204120 | N-Cyclohexylcarbonyl-N'-{4-[(6,7-di...)
Affinity DataIC50:  233nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184857(CHEMBL203227 | N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy...)
Affinity DataIC50:  234nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cell by transactivation enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184862(CHEMBL204409 | N-Benzyl-N'-{4-[(6,7-dimethoxy-4-qu...)
Affinity DataIC50:  303nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184857(CHEMBL203227 | N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy...)
Affinity DataIC50:  434nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184864(CHEMBL203279 | N-{4-[(6,7-Dimethoxy-4-quinazolinyl...)
Affinity DataIC50:  623nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184863(CHEMBL202919 | N-(2-Chlorobenzoyl)-N'-{4-[(6,7-dim...)
Affinity DataIC50:  637nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184868(CHEMBL378489 | N-Benzoyl-N'-{4-[(6,7-dimethoxy-4-q...)
Affinity DataIC50:  938nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed