Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50017898
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188092(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188095(1-(3,4-Dichloro-benzyl)-1H-imidazole | 1-(3,4-dich...)
Affinity DataIC50:  2.07E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188091(1-(3,5-dibromobenzyl)-1H-imidazole | CHEMBL211276)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188094(1-(3,5-dichlorobenzyl)-1H-imidazole | CHEMBL210125)
Affinity DataIC50:  3.34E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  3.76E+3nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188088(1-(4-bromobenzyl)-1H-imidazole | CHEMBL211207)
Affinity DataIC50:  6.76E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188093(1-(4-Nitro-benzyl)-1H-imidazole | 1-(4-nitrobenzyl...)
Affinity DataIC50:  7.17E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50008733(1-(4-Cyanobenzyl)-1H-imidazole | 4-((1H-imidazol-1...)
Affinity DataIC50:  7.67E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188086(4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...)
Affinity DataIC50:  8.22E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188087(1-(4-methyl-benzyl)-1H-imidazole | 1-(4-methylbenz...)
Affinity DataIC50:  8.81E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188090(1-(3,4-difluorobenzyl)-1H-imidazole | CHEMBL373588)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188092(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188089(1-(3,5-difluorobenzyl)-1H-imidazole | CHEMBL446946)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188095(1-(3,4-Dichloro-benzyl)-1H-imidazole | 1-(3,4-dich...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188096(1-(3,5-bis(trifluoromethyl)benzyl)-1H-imidazole | ...)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188094(1-(3,5-dichlorobenzyl)-1H-imidazole | CHEMBL210125)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188093(1-(4-Nitro-benzyl)-1H-imidazole | 1-(4-nitrobenzyl...)
Affinity DataIC50:  2.54E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188091(1-(3,5-dibromobenzyl)-1H-imidazole | CHEMBL211276)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM7887(1-Benzylimidazole (BI) | 1-benzyl-1H-imidazole | 1...)
Affinity DataIC50:  3.91E+4nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50008733(1-(4-Cyanobenzyl)-1H-imidazole | 4-((1H-imidazol-1...)
Affinity DataIC50:  4.03E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188087(1-(4-methyl-benzyl)-1H-imidazole | 1-(4-methylbenz...)
Affinity DataIC50:  5.06E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188088(1-(4-bromobenzyl)-1H-imidazole | CHEMBL211207)
Affinity DataIC50:  5.34E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188090(1-(3,4-difluorobenzyl)-1H-imidazole | CHEMBL373588)
Affinity DataIC50:  7.07E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188086(4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...)
Affinity DataIC50:  7.21E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188089(1-(3,5-difluorobenzyl)-1H-imidazole | CHEMBL446946)
Affinity DataIC50:  8.31E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50:  8.66E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM7887(1-Benzylimidazole (BI) | 1-benzyl-1H-imidazole | 1...)
Affinity DataIC50:  2.15E+5nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188096(1-(3,5-bis(trifluoromethyl)benzyl)-1H-imidazole | ...)
Affinity DataIC50:  2.45E+5nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed