Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50038011
TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202131(CHEMBL248356 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202144(CHEMBL395644 | N-(4-chloro-2-((4-ethoxy-1,3-dioxoi...)
Affinity DataEC50:  280nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50156070(CHEMBL366217 | N-(4-Chloro-2-[(1,3-dioxo-1,3-dihyd...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202127(CHEMBL247746 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202120(CHEMBL247948 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202130(CHEMBL397393 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50156061(CHEMBL365797 | CHEMBL556609 | N-(4-chloro-2-((1,3-...)
Affinity DataEC50:  250nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202124(CHEMBL245288 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202142(CHEMBL396918 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202135(CHEMBL245897 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202121(CHEMBL397648 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202118(CHEMBL430009 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202128(CHEMBL247950 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202134(CHEMBL398125 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202143(CHEMBL395675 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202117(CHEMBL395882 | N-(4-chloro-2-((4,5-dimethyl-1,3-di...)
Affinity DataEC50:  2.20E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202118(CHEMBL430009 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50:  5.70E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202120(CHEMBL247948 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50:  2.10E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202119((E)-N-(4-chloro-2-(3-oxo-3-phenylprop-1-enyl)pheny...)
Affinity DataEC50:  1.70E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202122(CHEMBL246058 | N-(4-chloro-2-(3-oxo-3-phenylpropyl...)
Affinity DataEC50:  4.50E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202124(CHEMBL245288 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202125(CHEMBL247548 | N-(4-bromo-2-((4,5-dimethyl-1,3-dio...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202123(CHEMBL394655 | N-(2-((1,3-dioxoisoindolin-2-yl)met...)
Affinity DataEC50:  1.40E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202129(CHEMBL247349 | N-(4-bromo-2-((4,5-dimethoxy-1,3-di...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202126(CHEMBL246724 | N-(2-((1,3-dioxoisoindolin-2-yl)met...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202127(CHEMBL247746 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50:  3.50E+4nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50156070(CHEMBL366217 | N-(4-Chloro-2-[(1,3-dioxo-1,3-dihyd...)
Affinity DataEC50:  250nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202131(CHEMBL248356 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50:  5.70E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202133(CHEMBL395389 | N-(4-bromo-2-((4-ethoxy-1,3-dioxois...)
Affinity DataEC50:  720nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202132(CHEMBL395645 | N-(4-chloro-2-((4,5-dimethoxy-1,3-d...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202135(CHEMBL245897 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202136(CHEMBL246935 | N-(4-bromo-2-((5-fluoro-1,3-dioxois...)
Affinity DataEC50:  930nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202130(CHEMBL397393 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202134(CHEMBL398125 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50:  2.30E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50156082(CHEMBL362969 | N-(4-bromo-2-((1,3-dioxoisoindolin-...)
Affinity DataEC50:  750nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202128(CHEMBL247950 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202139(CHEMBL246518 | N-(2-((1,3-dioxoisoindolin-2-yl)met...)
Affinity DataEC50:  1.39E+4nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50156061(CHEMBL365797 | CHEMBL556609 | N-(4-chloro-2-((1,3-...)
Affinity DataEC50:  250nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202137(CHEMBL246727 | N-(2-((1,3-dioxoisoindolin-2-yl)met...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202141(CHEMBL245854 | N-(4-chloro-2-((3,5-dichloro-N-ethy...)
Affinity DataEC50:  4.70E+5nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202140(CHEMBL395388 | N-(4-chloro-2-((5-fluoro-1,3-dioxoi...)
Affinity DataEC50:  330nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202142(CHEMBL396918 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202121(CHEMBL397648 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50:  260nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202143(CHEMBL395675 | N-(4-chloro-2-((1,3-dioxoisoindolin...)
Affinity DataEC50:  1.90E+3nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50156082(CHEMBL362969 | N-(4-bromo-2-((1,3-dioxoisoindolin-...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed