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Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50019792
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207760(CHEMBL391374 | [4-(2-hydroxy-ethyl)-piperazin-1-yl...)
Affinity DataIC50:  43nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207768((4-methyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-y...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207768((4-methyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-y...)
Affinity DataIC50:  81nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207772(CHEMBL245590 | adamantan-1-yl-piperidin-1-yl-metha...)
Affinity DataIC50:  134nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207772(CHEMBL245590 | adamantan-1-yl-piperidin-1-yl-metha...)
Affinity DataIC50:  193nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207799(CHEMBL245393 | adamantan-2-yl-piperidin-1-yl-metha...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207787(CHEMBL428931 | adamantan-1-yl-(octahydro-isoquinol...)
Affinity DataIC50:  230nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207776(CHEMBL396928 | adamantan-1-yl-(4-ethyl-piperazin-1...)
Affinity DataIC50:  300nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207795(CHEMBL246952 | adamantan-1-yl-(3,4-dihydro-2H-quin...)
Affinity DataIC50:  481nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207767(CHEMBL245509 | adamantan-1-yl-[4-(2-hydroxy-ethyl)...)
Affinity DataIC50:  494nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207788((3R,5R)-adamantan-1-yl(pyrrolidin-1-yl)methanone |...)
Affinity DataIC50:  498nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207760(CHEMBL391374 | [4-(2-hydroxy-ethyl)-piperazin-1-yl...)
Affinity DataIC50:  498nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207770((4-ethyl-piperazin-1-yl)-[3-(4-methoxy-phenyl)-ada...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207800(CHEMBL396366 | adamantan-1-yl-(4-methyl-piperazin-...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207776(CHEMBL396928 | adamantan-1-yl-(4-ethyl-piperazin-1...)
Affinity DataIC50:  756nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207787(CHEMBL428931 | adamantan-1-yl-(octahydro-isoquinol...)
Affinity DataIC50:  846nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207790((3-benzyl-adamantan-1-yl)-(4-ethyl-piperazin-1-yl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207757((4-tert-butylcyclohexyl)(4-ethylpiperazin-1-yl)met...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207767(CHEMBL245509 | adamantan-1-yl-[4-(2-hydroxy-ethyl)...)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207789((4-benzyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-y...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207795(CHEMBL246952 | adamantan-1-yl-(3,4-dihydro-2H-quin...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207769((4-phenethyl-piperazin-1-yl)-(3-p-tolyl-adamantan-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207781(CHEMBL247179 | phenyl-[4-(3-p-tolyl-adamantane-1-c...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207773(CHEMBL245511 | [4-(2-methoxy-ethyl)-piperazin-1-yl...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207765(2-adamantan-1-yl-1-(4-ethyl-piperazin-1-yl)-ethano...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207786(CHEMBL439383 | adamantan-1-yl-(3,4-dihydro-1H-isoq...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207774(CHEMBL245302 | adamantan-1-yl-(4-pyridin-4-ylmethy...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207797(1-(4-ethylpiperazin-1-yl)-2-phenylethanone | CHEMB...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207803(CHEMBL394929 | adamantan-1-yl-(4-benzyl-piperazin-...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207777((4-phenyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-y...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207784((3-hydroxy-adamantan-1-yl)-piperidin-1-yl-methanon...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207756((4-phenylmethanesulfonyl-piperazin-1-yl)-(3-p-toly...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207779((4-pyridin-4-ylmethyl-piperazin-1-yl)-(3-p-tolyl-a...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207783(CHEMBL391335 | adamantan-1-yl-piperazin-1-yl-metha...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207766(3-methyl-2-[4-(3-p-tolyl-adamantane-1-carbonyl)-pi...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207780((4-ethylpiperazin-1-yl)(1-(4-fluorophenyl)cyclopen...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207792(CHEMBL245510 | adamantan-1-yl-[4-(2-methoxy-ethyl)...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207763(CHEMBL245988 | adamantan-1-yl-(4-phenylmethanesulf...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207801((4-ethylpiperazin-1-yl)(3-methyl-1H-inden-2-yl)met...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207757((4-tert-butylcyclohexyl)(4-ethylpiperazin-1-yl)met...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207758(2-[4-(adamantane-1-carbonyl)-piperazin-1-yl]-3-met...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207798(CHEMBL396925 | [4-(adamantane-1-carbonyl)-piperazi...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207761(CHEMBL246977 | phenyl-[4-(3-p-tolyl-adamantane-1-c...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207785(CHEMBL396611 | bicyclo[2.2.1]heptan-2-yl(4-ethylpi...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207771(CHEMBL245708 | adamantan-1-yl-(4-phenethyl-piperaz...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207794(3-cyclohexyl-1-(4-ethylpiperazin-1-yl)propan-1-one...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207775((4-ethyl-piperazin-1-yl)-(3-hydroxy-adamantan-1-yl...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207802(CHEMBL248168 | cyclohexyl(4-ethylpiperazin-1-yl)me...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207778((4-benzenesulfonyl-piperazin-1-yl)-(3-p-tolyl-adam...)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207791(CHEMBL245954 | adamantan-1-yl-(4-phenyl-piperazin-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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