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Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50020680
TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216395(CHEMBL231032 | N-(2-(4-(2-fluorophenyl)piperazin-1...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216402(CHEMBL230925 | N-(2-(4-(4-nitrophenyl)piperazin-1-...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216390(CHEMBL231645 | N-(2-(4-benzylpiperazin-1-yl)-2-oxo...)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216397(CHEMBL395958 | isoquinolinesulfon-5-yl-{2-[4-(4-ac...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216409(CHEMBL231658 | N-(2-oxo-2-(4-phenethylpiperazin-1-...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216388(CHEMBL230612 | N-(2-(4-(4-fluorophenyl)piperazin-1...)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216384(CHEMBL231244 | isoquinolinesulfon-5-yl-[2-(4-napht...)
Affinity DataIC50:  90nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216372(CHEMBL395076 | isoquinolinesulfon-5-yl-[2-(4-benzy...)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216373(CHEMBL231441 | isoquinolinesulfon-5-yl-[2-oxo-2-(4...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216377(CHEMBL395737 | isoquinolinesulfon-5-yl-[3-oxo-3-(4...)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216400(CHEMBL230076 | isoquinolinesulfon-5-yl-[2-(4-benzy...)
Affinity DataIC50:  900nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216386(CHEMBL395710 | isoquinolinesulfon-5-yl-{2-[4-(4-me...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216403(CHEMBL230295 | N-(2-oxo-2-(4-phenylpiperazin-1-yl)...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216375(CHEMBL397423 | isoquinolinesulfon-5-yl-{2-[4-(4-am...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216404(CHEMBL231138 | isoquinolinesulfon-5-yl-{2-[4-(2,5-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216408(CHEMBL231137 | isoquinolinesulfon-5-yl-{2-[4-(2,3-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216411(CHEMBL231644 | naphthalenesulfon-1-yl-[2-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216391(CHEMBL231136 | isoquinolinesulfon-5-yl-{2-[4-(3,4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216407(CHEMBL395075 | isoquinolinesulfon-5-yl-[2-oxo-2-(4...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216389(CHEMBL231643 | N-(2-(4-(4-cyanophenyl)piperazin-1-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216378(CHEMBL231540 | isoquinolinesulfon-5-yl-[2-oxo-2-(4...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216398(CHEMBL425820 | naphthalenesulfon-1-yl-[2-(4-benzyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216406(CHEMBL390054 | N-(2-(4-(4-fluorophenyl)piperazin-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216382(CHEMBL390887 | N-(2-(4-(2-fluorophenyl)piperazin-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216413(CHEMBL397196 | isoquinolinesulfon-5-yl-{2-[4-(4-me...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216393(CHEMBL231242 | N-(2-(4-(2-fluorophenyl)piperazin-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216385(CHEMBL230926 | naphthalenesulfon-1-yl-{2-[4-(4-flu...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216387(CHEMBL397195 | isoquinolinesulfon-5-yl-{2-[4-(4-tr...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216381(CHEMBL230827 | isoquinolinesulfon-5-yl-{3-[4-(4-fl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216399(CHEMBL396009 | isoquinolinesulfon-5-yl-{2-oxo-2-[4...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216392(CHEMBL230928 | isoquinolinesulfon-5-yl-{2-[4-(4-fl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216401(CHEMBL389354 | N-(2-(4-(3-fluorophenyl)piperazin-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216374(CHEMBL231033 | isoquinolinesulfon-5-yl-{2-[4-(2-fl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216394(CHEMBL389547 | isoquinolinesulfon-5-yl-{2-[4-(2,4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216383(CHEMBL231341 | naphthalenesulfon-1-yl-{2-[4-(2-flu...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216396(CHEMBL231543 | naphthalenesulfon-1-yl-[2-(4-phenyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216379(CHEMBL231343 | isoquinolinesulfon-5-yl-{2-[4-(4-ch...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216376(CHEMBL231029 | isoquinolinesulfon-5-yl-{3-[4-(4-ni...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216410(CHEMBL390888 | isoquinolinesulfon-5-yl-{2-[4-(4-ch...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216380(CHEMBL387801 | naphthalenesulfon-1-yl-[2-oxo-2-(4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216412(CHEMBL231440 | isoquinolinesulfon-5-yl-{2-[4-(4-io...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50216405(CHEMBL231439 | isoquinolinesulfon-5-yl-{2-[4-(4-br...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed