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Found 2 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50216395'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50216395(CHEMBL231032 | N-(2-(4-(2-fluorophenyl)piperazin-1...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50216395(CHEMBL231032 | N-(2-(4-(2-fluorophenyl)piperazin-1...)
Affinity DataIC50:  12.6nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed