Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50020690
TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216485(5-benzyl-6-(4-(3-chlorophenyl)piperidin-1-yl)pyrim...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216493(5-benzyl-6-(3-phenylpiperidin-1-yl)pyrimidine-2,4(...)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216480(5-benzyl-6-(4-(2-methoxyphenyl)piperidin-1-yl)pyri...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216491(5-benzyl-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(...)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216488(5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216474(5-(3-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216479(5-benzyl-6-(4-(3-methoxyphenyl)piperidin-1-yl)pyri...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216494(5-(3-bromobenzyl)-6-(4-phenylpiperidin-1-yl)pyrimi...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216476(5-(3-chlorobenzyl)-6-(4-benzylpiperidin-1-yl)-3-me...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216482(5-benzyl-6-(4-benzylpiperidin-1-yl)pyrimidine-2,4(...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216489(5-benzyl-3-methyl-6-(4-phenylpiperidin-1-yl)pyrimi...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216473(5-benzyl-6-(4-benzylpiperidin-1-yl)-3-methylpyrimi...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216478(5-(4-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216477(5-(2-bromobenzyl)-6-(4-benzylpiperidin-1-yl)-3-met...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216495(3-((2,4-dioxo-6-(4-phenylpiperidin-1-yl)-1,2,3,4-t...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216492(5-benzyl-6-(4-(4-methoxyphenyl)piperidin-1-yl)pyri...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216490(CHEMBL231500 | N-(4-(1-(5-benzyl-2,6-dioxo-1,2,3,6...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216483(5-benzyl-6-(3-phenylpyrrolidin-1-yl)pyrimidine-2,4...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216488(5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  50nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216494(5-(3-bromobenzyl)-6-(4-phenylpiperidin-1-yl)pyrimi...)
Affinity DataKi:  65nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216481(5-benzyl-3-methyl-6-(4-phenoxypiperidin-1-yl)pyrim...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216491(5-benzyl-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(...)
Affinity DataKi:  93nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216474(5-(3-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  96nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216485(5-benzyl-6-(4-(3-chlorophenyl)piperidin-1-yl)pyrim...)
Affinity DataKi:  97nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216473(5-benzyl-6-(4-benzylpiperidin-1-yl)-3-methylpyrimi...)
Affinity DataKi:  100nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216497(5-benzyl-6-(4-(4-chlorophenyl)piperidin-1-yl)pyrim...)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216476(5-(3-chlorobenzyl)-6-(4-benzylpiperidin-1-yl)-3-me...)
Affinity DataKi:  135nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216482(5-benzyl-6-(4-benzylpiperidin-1-yl)pyrimidine-2,4(...)
Affinity DataKi:  150nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216496(5-benzyl-3-methyl-6-(4-phenethylpiperidin-1-yl)pyr...)
Affinity DataKi:  154nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216479(5-benzyl-6-(4-(3-methoxyphenyl)piperidin-1-yl)pyri...)
Affinity DataKi:  158nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216489(5-benzyl-3-methyl-6-(4-phenylpiperidin-1-yl)pyrimi...)
Affinity DataKi:  190nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216493(5-benzyl-6-(3-phenylpiperidin-1-yl)pyrimidine-2,4(...)
Affinity DataKi:  225nMAssay Description:Activity at human GR expressed in SW1353 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216487(6-(4-benzoylpiperidin-1-yl)-5-benzyl-3-methylpyrim...)
Affinity DataKi:  227nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216478(5-(4-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  260nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMineralocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216480(5-benzyl-6-(4-(2-methoxyphenyl)piperidin-1-yl)pyri...)
Affinity DataKi:  298nMAssay Description:Displacement of [3H]aldosterone from mineralocorticoid receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216477(5-(2-bromobenzyl)-6-(4-benzylpiperidin-1-yl)-3-met...)
Affinity DataKi:  300nMAssay Description:Antagonist activity at human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216475(5-benzyl-6-(4-benzyl-4-hydroxypiperidin-1-yl)-3-me...)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216486(5-benzyl-3-methyl-6-(4-phenylpiperazin-1-yl)pyrimi...)
Affinity DataKi:  470nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMineralocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216485(5-benzyl-6-(4-(3-chlorophenyl)piperidin-1-yl)pyrim...)
Affinity DataKi:  527nMAssay Description:Displacement of [3H]aldosterone from mineralocorticoid receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMineralocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216474(5-(3-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  585nMAssay Description:Displacement of [3H]aldosterone from mineralocorticoid receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMineralocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216491(5-benzyl-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(...)
Affinity DataKi:  930nMAssay Description:Displacement of [3H]aldosterone from mineralocorticoid receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMineralocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216479(5-benzyl-6-(4-(3-methoxyphenyl)piperidin-1-yl)pyri...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H]aldosterone from mineralocorticoid receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMineralocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216488(5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  3.49E+3nMAssay Description:Displacement of [3H]aldosterone from mineralocorticoid receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216484(5-(3-(trifluoromethyl)benzyl)-6-(4-hydroxypiperidi...)
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProgesterone receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50216474(5-(3-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...)
Affinity DataKi:  7.05E+3nMAssay Description:Displacement of [3H]progesterone from progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed