Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50021083
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220766(5-(7-(4-morpholinobutoxy)-1,4-dihydroindeno[1,2-c]...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220753(5-(6,7-dimethoxy-1,4-dihydro-indeno[1,2-c]pyrazol-...)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220762(5-(7-(3-(1,4-oxazepan-4-yl)propoxy)-1,4-dihydroind...)
Affinity DataIC50:  0.920nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220757(5-(7-(3-(piperidin-4-yl)propoxy)-1,4-dihydroindeno...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220751(5-(7-(3-((2S,6R)-2,6-dimethylmorpholino)propoxy)-1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220768(5-(7-(3-(1H-imidazol-1-yl)propoxy)-1,4-dihydroinde...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220755(5-(6-methoxy-7-(2-(4-methylthiazol-5-yl)ethoxy)-1,...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220774(5-(7-(4-morpholinobutyl)-1,4-dihydroindeno[1,2-c]p...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220765(5-(7-(5-morpholinopentyloxy)-1,4-dihydroindeno[1,2...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220754(5-(7-(3-(4-methylpiperazin-1-yl)propoxy)-1,4-dihyd...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220752(5-(7-(4-(4-acetylpiperazin-1-yl)butoxy)-1,4-dihydr...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214577(4'-(6,7-dimethoxy-1,4-dihydro-indeno[1,2-c]pyrazol...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220756(5-(7-(2-(2-morpholinoethoxy)ethoxy)-1,4-dihydroind...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220761(5-(7-methoxy-6-(2-(4-methylthiazol-5-yl)ethoxy)-1,...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220771(5-(7-(3-(piperidin-1-yl)propoxy)-1,4-dihydroindeno...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220778(5-(7-(2-hydroxyethoxy)-6-methoxy-1,4-dihydroindeno...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220770(5-(6-methoxy-7-(2-morpholinoethoxy)-1,4-dihydroind...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220764(5-(6-(2-hydroxyethoxy)-7-methoxy-1,4-dihydroindeno...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220772(5-(7-(3-morpholinopropoxy)-1,4-dihydroindeno[1,2-c...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220776(5-(7-methoxy-6-(pyridin-2-ylmethoxy)-1,4-dihydroin...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220775(5-(7-methoxy-6-(2-morpholinoethoxy)-1,4-dihydroind...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220777(5-(7-(2-morpholinoethoxy)-1,4-dihydroindeno[1,2-c]...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220769(5-(6-(3-morpholinopropoxy)-1,4-dihydroindeno[1,2-c...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220759(5-(7-(2-(4-methylthiazol-5-yl)ethoxy)-1,4-dihydroi...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220760(5-(6-(2-morpholinoethoxy)-1,4-dihydroindeno[1,2-c]...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220767(5-(7-(2-morpholinoethylamino)-1,4-dihydroindeno[1,...)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220758(CHEMBL249116 | N-(3-(6-cyanopyridin-3-yl)-1,4-dihy...)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220763(5-(7-(3-(thiophen-2-yl)propoxy)-1,4-dihydroindeno[...)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed