Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50037995
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225877BDBM50225877((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-tetrahyd...)
Affinity DataIC50: 1.90nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225880BDBM50225880((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataIC50: 2.5nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225878BDBM50225878((R)-benzyl 3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hy...)
Affinity DataIC50: 3.20nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225885BDBM50225885((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-tetrahyd...)
Affinity DataIC50: 5.30nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225877BDBM50225877((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-tetrahyd...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138530BDBM50138530((2R,3S,4R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...)
Affinity DataIC50: 8.20nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225881BDBM50225881((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataIC50: 9nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225881BDBM50225881((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225880BDBM50225880((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225883BDBM50225883(endo-(2R,3R,4S,5R)-2-(6-(7-aza-bicyclo[2.2.1]hepta...)
Affinity DataIC50: 35nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225883BDBM50225883(endo-(2R,3R,4S,5R)-2-(6-(7-aza-bicyclo[2.2.1]hepta...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138530BDBM50138530((2R,3S,4R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225882BDBM50225882((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataIC50: 68nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225885BDBM50225885((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-tetrahyd...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225879BDBM50225879(1-((R)-3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydrox...)
Affinity DataIC50: 85nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21220BDBM21220(CHEMBL464859 | N-Ethylcarboxamidoadenosine | Adeno...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225882BDBM50225882((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataKi:  164nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225876BDBM50225876((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataIC50: 254nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225878BDBM50225878((R)-benzyl 3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hy...)
Affinity DataKi:  288nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225884BDBM50225884((R)-tert-butyl 3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5...)
Affinity DataIC50: 380nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225876BDBM50225876((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataKi:  783nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225879BDBM50225879(1-((R)-3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydrox...)
Affinity DataKi:  803nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225884BDBM50225884((R)-tert-butyl 3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5...)
Affinity DataKi:  929nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225877BDBM50225877((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-tetrahyd...)
Affinity DataKi:  5.50E+3nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225883BDBM50225883(endo-(2R,3R,4S,5R)-2-(6-(7-aza-bicyclo[2.2.1]hepta...)
Affinity DataKi:  7.80E+3nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225885BDBM50225885((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-tetrahyd...)
Affinity DataKi:  9.70E+3nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225880BDBM50225880((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataKi:  3.47E+4nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225881BDBM50225881((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225878BDBM50225878((R)-benzyl 3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hy...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225879BDBM50225879(1-((R)-3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydrox...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225884BDBM50225884((R)-tert-butyl 3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225876BDBM50225876((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138530BDBM50138530((2R,3S,4R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225882BDBM50225882((1S,2R,4S)-2-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hyd...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]ZM-241385 from adenosine A2A receptor expressed in PC12 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed