Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 2782
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24572BDBM24572((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]heptan-2-...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24573BDBM24573((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridec...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24574BDBM24574((2R)-1-[(2S,3R)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50: 180nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24575BDBM24575((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 210nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24569BDBM24569(Orlistat derivative, 15f | (2S)-1-[(2S,3S)-3-ethyl...)
Affinity DataIC50: 230nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24570BDBM24570((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...)
Affinity DataIC50: 280nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24576BDBM24576((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24571BDBM24571((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]heptan-2-...)
Affinity DataIC50: 300nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24577BDBM24577((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]-3-{[(4-m...)
Affinity DataIC50: 370nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24578BDBM24578((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridec...)
Affinity DataIC50: 400nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24579BDBM24579((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 450nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24580BDBM24580((2S,5E)-6-(4-fluorophenyl)-1-[(2S,3S)-3-hexyl-4-ox...)
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24581BDBM24581((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...)
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24582BDBM24582((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]propan-2-...)
Affinity DataIC50: 520nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24583BDBM24583((2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50: 680nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24569BDBM24569(Orlistat derivative, 15f | (2S)-1-[(2S,3S)-3-ethyl...)
Affinity DataIC50: 790nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24585BDBM24585((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...)
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24586BDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50: 1.02E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24587BDBM24587((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50: 1.04E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24567BDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 1.35E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24588BDBM24588((1R)-1-{[(2S,3S)-3-butyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50: 1.35E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24586BDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50: 1.72E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24590BDBM24590((2S)-1-[(2S,3S)-3-octyl-4-oxooxetan-2-yl]undecan-2...)
Affinity DataIC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24591BDBM24591((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 3.67E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24592BDBM24592((2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50: 6.24E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24593BDBM24593((2S)-1-[(2R,3R)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50: 9.74E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24594BDBM24594((2S)-1-[(2S,3S)-3-methyl-4-oxooxetan-2-yl]tridecan...)
Affinity DataIC50: 1.08E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24595BDBM24595((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50: 1.35E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetFatty acid synthase [2202-2509](Human)
The Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 24596BDBM24596((2S)-1-[(2R,3R)-3-methyl-4-oxooxetan-2-yl]tridecan...)
Affinity DataIC50: 4.51E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed