Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 2925
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26113BDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26119BDBM26119(2-[4-(methoxycarbonyl)pyridin-2-yl]pyridine-4-carb...)
Affinity DataIC50: 6.60E+3nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26120BDBM26120(pyrimidine-4,6-dicarboxylic acid | pyrimidine anal...)
Affinity DataIC50: 2.70E+4nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 19130BDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 2.80E+4nMpH: 7.5 T: 2°CAssay Description:For compounds which were shown to inhibit FDH, a MALDI-TOF-MS inhibition assay was employed. After incubation, the diluted assay mixture was then mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26110BDBM26110(N,3-dihydroxybenzamide | aromatic hydroxamic acid,...)
Affinity DataIC50: 2.80E+4nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26106BDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 7.80E+4nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26108BDBM26108((2R)-2-(formamidoformic acid)-4-phenylbutanoic aci...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26116BDBM26116(Dipicolinate | CHEMBL284104 | pyridine-2,6-dicarbo...)
Affinity DataIC50: 1.20E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26114BDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataIC50: 1.80E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26111BDBM26111(N,5-dihydroxy-2-methoxybenzamide | aromatic hydrox...)
Affinity DataIC50: 2.30E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26107BDBM26107((2R)-2-(formamidoformic acid)-3-phenylpropanoic ac...)
Affinity DataIC50: 3.20E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26112BDBM26112(N,5-dihydroxy-2-phenoxybenzamide | aromatic hydrox...)
Affinity DataIC50: 3.60E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 5.40E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26121BDBM26121(Succinic acid, 6 | butanedioic acid | Succinate | ...)
Affinity DataIC50: 7.10E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26122BDBM26122(FUMARIC ACID | Fumarate | (2E)-but-2-enedioic acid...)
Affinity DataIC50: 1.60E+6nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26115BDBM26115(pyridine-2,3-dicarboxylic acid | CHEMBL286204 | Qu...)
Affinity DataIC50: 5.00E+6nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26109BDBM26109(butanoic acid | Butyrate | butanoic acid, 4)
Affinity DataIC50: 1.00E+7nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26117BDBM26117(pyridine-3,4-dicarboxylic acid | pyridine carboxyl...)
Affinity DataIC50: 1.00E+7nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandChemical structure of BindingDB Monomer ID 26118BDBM26118(pyridine-3,5-dicarboxylic acid | pyridine carboxyl...)
Affinity DataIC50: 1.00E+7nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed