Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 2925
TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  1.40E+3nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26119(2-[4-(methoxycarbonyl)pyridin-2-yl]pyridine-4-carb...)
Affinity DataIC50:  6.60E+3nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26120(pyrimidine analogue, 8 | pyrimidine-4,6-dicarboxyl...)
Affinity DataIC50:  2.70E+4nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  2.80E+4nMpH: 7.5 T: 37°CAssay Description:For compounds which were shown to inhibit FDH, a MALDI-TOF-MS inhibition assay was employed. After incubation, the diluted assay mixture was then mix...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26110(N,3-dihydroxybenzamide | aromatic hydroxamic acid,...)
Affinity DataIC50:  2.80E+4nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  7.80E+4nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26108((2R)-2-(formamidoformic acid)-4-phenylbutanoic aci...)
Affinity DataIC50:  1.00E+5nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26116(CHEMBL284104 | Dipicolinate | pyridine carboxylate...)
Affinity DataIC50:  1.20E+5nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)
Affinity DataIC50:  1.80E+5nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26111(N,5-dihydroxy-2-methoxybenzamide | aromatic hydrox...)
Affinity DataIC50:  2.30E+5nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26107((2R)-2-(formamidoformic acid)-3-phenylpropanoic ac...)
Affinity DataIC50:  3.20E+5nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26112(N,5-dihydroxy-2-phenoxybenzamide | aromatic hydrox...)
Affinity DataIC50:  3.60E+5nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  5.40E+5nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  7.10E+5nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26122((2E)-but-2-enedioic acid | FUMARIC ACID | Fumarate...)
Affinity DataIC50:  1.60E+6nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26115(CHEMBL286204 | Quinolinate | Quinolinic acid | pyr...)
Affinity DataIC50: >5.00E+6nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26109(Butyrate | butanoic acid | butanoic acid, 4)
Affinity DataIC50: >1.00E+7nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26117(pyridine carboxylate, 6e | pyridine-3,4-dicarboxyl...)
Affinity DataIC50: >1.00E+7nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26118(pyridine carboxylate, 6f | pyridine-3,5-dicarboxyl...)
Affinity DataIC50: >1.00E+7nMpH: 7.5 T: 37°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed