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Found 28 Enz. Inhib. hit(s) with all data for entry = 50038745
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247911(2-(4-Pyridyl)-isothiazol-3(2H)-one | CHEMBL499919)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247911(2-(4-Pyridyl)-isothiazol-3(2H)-one | CHEMBL499919)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247615(2-(3,4,5-trifluorophenyl)isothiazol-3(2H)-one | CH...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50292429(2-Hydroxy-6-pentadecyl-benzoic acid | 2-Pentadecyl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant His-tagged HAT p300 expressed in Sf21-Baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247616(2-(3-chloro-2-fluorophenyl)isothiazol-3(2H)-one | ...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247912(2-(4-Dimethylaminoaniline)-isothiazol-3(2H)-one | ...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50241990(CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of HAT PCAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50241990(CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of HAT p300More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50037078(2-(Phenyl)-isothiazolo[5,4-b]pyridin-3(2H)-one | 2...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247913(2-(3-Pyridyl)-isothiazol-3(2H)-one | CHEMBL487498)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247909(2-(4-Morpholinoaniline)-isothiazol-3(2H)-one | CHE...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247909(2-(4-Morpholinoaniline)-isothiazol-3(2H)-one | CHE...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247913(2-(3-Pyridyl)-isothiazol-3(2H)-one | CHEMBL487498)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247584(2-(2-Pyridyl)-isothiazol-3(2H)-one | CHEMBL489494)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247600(5-chloro-4-methyl-2-phenylisothiazol-3(2H)-one | C...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50240683(2-Phenyl-isothiazol-3-one | 2-phenylisothiazol-3(2...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50240683(2-Phenyl-isothiazol-3-one | 2-phenylisothiazol-3(2...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247584(2-(2-Pyridyl)-isothiazol-3(2H)-one | CHEMBL489494)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of GST-fused recombinant HAT p300 expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247588(4-methyl-2-phenylisothiazol-3(2H)-one | CHEMBL4742...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247590(4-Azidomethyl-2-phenyl-isothiazol-3(2H)-one | CHEM...)
Affinity DataIC50:  4.27E+4nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247585(5-Azidomethyl-2-phenylisothiazol-3(2H)-one | CHEMB...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247589(4-Methoxymethyl-2-phenyl-isothiazol-3(2H)-one | CH...)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247910(5-Hydroxymethyl-2-phenylisothiazol-3(2H)-one | CHE...)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247914(5-Acetoxymethyl-2-phenylisothiazol-3(2H)-one | CHE...)
Affinity DataIC50:  1.62E+5nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247587(2,5-diphenylisothiazol-3(2H)-one | CHEMBL500224 | ...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247586(5-Methyl-2-N-Phenylisothiazol-3(2H)-one | CHEMBL48...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247583(5-Phenylureidomethyl-2-phenylisothiazol-3(2H)-one ...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50247614(4-Methyl-5-methoxy-2-phenyl-isothiazol-3(2H)-one |...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of GST-fused recombinant HAT PCAF expressed in Escherichia coli by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed