Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50028100
TargetTranscription factor p65(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50135482(1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataEC50:  380nMAssay Description:Potentiation of TNFalpha-induced NFkappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50277067(1-(8-chloro-5-methoxy-2-(thiophen-2-yl)quinazolin-...)
Affinity DataEC50:  310nMAssay Description:Potentiation of TNFalpha-induced NFkappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50135483(1-(6-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataEC50:  9.80E+3nMAssay Description:Induction of NFkappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50277067(1-(8-chloro-5-methoxy-2-(thiophen-2-yl)quinazolin-...)
Affinity DataEC50:  2.40E+3nMAssay Description:Induction of NFkappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50135482(1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataEC50:  1.60E+3nMAssay Description:Induction of NFkappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50135483(1-(6-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataEC50:  4.20E+4nMAssay Description:Potentiation of TNFalpha-induced NFkappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed