Compile Data Set for Download or QSAR
maximum 50k data
Found 81 Enz. Inhib. hit(s) with all data for entry = 50028516
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277718(2-(3-(7-hydroxypyrazolo[1,5-a]quinolin-3-yl)propan...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277717(2-(3-(6-chloro-7-hydroxynaphtho[2,1-d]isoxazol-3-y...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277581(2-(3-(7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propana...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277715(2-(3-(7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propana...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277714(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277580(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277753(2-[3-(7-Hydroxy-benzo[d]imidazo[2,1-b]thiazol-2-yl...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277579(2-(3-(7-hydroxy-2H-benzo[g]indazol-3-yl)propanamid...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277716(2-(3-(6-fluoro-7-hydroxynaphtho[2,1-d]isoxazol-3-y...)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277633(2-(3-(7-hydroxy-[1,2,3]triazolo[1,5-a]quinolin-3-y...)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277635(2-[3-(7-Hydroxy-benzo[d]imidazo[2,1-b]thiazol-2-yl...)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277754(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277582(2-(3-(7-hydroxy-4,5-dihydropyrazolo[1,5-a]quinolin...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277543(2-(3-(7-hydroxy-4,5-dihydro-2H-benzo[g]indazol-3-y...)
Affinity DataIC50:  17nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277677(2-(3-(3H-benzo[e]indazol-7-yl)propanamido)benzoic ...)
Affinity DataIC50:  18nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264232(2-(3-(6-hydroxynaphthalen-2-yl)propanamido)benzoic...)
Affinity DataIC50:  21nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277755(2-[3-(7-Hydroxy-benzo[d]imidazo[2,1-b]thiazol-2-yl...)
Affinity DataIC50:  23nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277636(2-(3-Benzo[d]imidazo[2,1-b]thiazol-2-yl-propionyla...)
Affinity DataIC50:  31nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277544(2-(3-(7-hydroxy-2-methyl-4,5-dihydro-2H-benzo[g]in...)
Affinity DataIC50:  35nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277578(2-(3-(7-hydroxy-1-methyl-4,5-dihydro-1H-benzo[g]in...)
Affinity DataIC50:  130nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277676(2-(3-(8-hydroxy-5-methyl-6-oxo-5,6-dihydrophenanth...)
Affinity DataIC50:  340nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277634(2-(3-(7-hydroxy-5-methyl-4-oxo-4,5-dihydro-[1,2,3]...)
Affinity DataIC50:  360nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277674(2-(3-(6-hydroxy-4H-indeno[2,1-d]isoxazol-3-yl)prop...)
Affinity DataIC50:  380nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277581(2-(3-(7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propana...)
Affinity DataIC50:  990nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277633(2-(3-(7-hydroxy-[1,2,3]triazolo[1,5-a]quinolin-3-y...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277717(2-(3-(6-chloro-7-hydroxynaphtho[2,1-d]isoxazol-3-y...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277716(2-(3-(6-fluoro-7-hydroxynaphtho[2,1-d]isoxazol-3-y...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277675(2-(3-(6-hydroxy-1-methyl-1,4-dihydroindeno[1,2-c]p...)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277580(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277636(2-(3-Benzo[d]imidazo[2,1-b]thiazol-2-yl-propionyla...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277676(2-(3-(8-hydroxy-5-methyl-6-oxo-5,6-dihydrophenanth...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277579(2-(3-(7-hydroxy-2H-benzo[g]indazol-3-yl)propanamid...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using montelukast substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277580(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using montelukast substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277674(2-(3-(6-hydroxy-4H-indeno[2,1-d]isoxazol-3-yl)prop...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277579(2-(3-(7-hydroxy-2H-benzo[g]indazol-3-yl)propanamid...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277582(2-(3-(7-hydroxy-4,5-dihydropyrazolo[1,5-a]quinolin...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using montelukast substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277714(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277755(2-[3-(7-Hydroxy-benzo[d]imidazo[2,1-b]thiazol-2-yl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277753(2-[3-(7-Hydroxy-benzo[d]imidazo[2,1-b]thiazol-2-yl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277715(2-(3-(7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propana...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277578(2-(3-(7-hydroxy-1-methyl-4,5-dihydro-1H-benzo[g]in...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277582(2-(3-(7-hydroxy-4,5-dihydropyrazolo[1,5-a]quinolin...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277718(2-(3-(7-hydroxypyrazolo[1,5-a]quinolin-3-yl)propan...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277674(2-(3-(6-hydroxy-4H-indeno[2,1-d]isoxazol-3-yl)prop...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using montelukast substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277543(2-(3-(7-hydroxy-4,5-dihydro-2H-benzo[g]indazol-3-y...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using montelukast substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277543(2-(3-(7-hydroxy-4,5-dihydro-2H-benzo[g]indazol-3-y...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277714(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using montelukast substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277754(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using montelukast substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277754(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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