Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 3177
LigandChemical structure of BindingDB Monomer ID 29034BDBM29034(cyanohydroxybutenamide, 24)
Affinity DataKi:  2.70nM IC50: 22nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29026BDBM29026(CHEMBL142996 | cyanocyclopropylpropenamide, 11)
Affinity DataKi:  7nM IC50: 53nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29025BDBM29025(cyanohydroxybutenamide, 10)
Affinity DataKi:  11nM IC50: 90nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29024BDBM29024(CHEMBL141732 | cyanocyclopropylpropenamide, 4)
Affinity DataKi:  14nM IC50: 117nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29037BDBM29037(cyanohydroxybutenamide, 27)
Affinity DataKi:  16nM IC50: 130nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29039BDBM29039(cyanohydroxybutenamide, 29)
Affinity DataKi:  16nM IC50: 130nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29028BDBM29028(cyanohydroxybutenamide, 18)
Affinity DataKi:  21nM IC50: 170nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29027BDBM29027(cyanohydroxybutenamide, 17)
Affinity DataKi:  22nM IC50: 180nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29035BDBM29035(cyanohydroxybutenamide, 25)
Affinity DataKi:  23nM IC50: 190nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29029BDBM29029(cyanohydroxybutenamide, 19)
Affinity DataKi:  25nM IC50: 200nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29036BDBM29036(cyanohydroxybutenamide, 26)
Affinity DataKi:  25nM IC50: 200nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14712BDBM14712(A77 1726 | CHEMBL973 | (2Z)-2-cyano-3-hydroxy-N-[4...)
Affinity DataKi:  32nM IC50: 261nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29038BDBM29038(cyanohydroxybutenamide, 28)
Affinity DataKi:  39nM IC50: 320nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29030BDBM29030(cyanohydroxybutenamide, 20)
Affinity DataKi:  40nM IC50: 330nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29032BDBM29032(cyanohydroxybutenamide, 22)
Affinity DataKi:  190nM IC50: 1.52E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29027BDBM29027(cyanohydroxybutenamide, 17)
Affinity DataKi:  480nM ΔG°:  -36.1kJ/mole IC50: 4.00E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29028BDBM29028(cyanohydroxybutenamide, 18)
Affinity DataKi:  730nM ΔG°:  -35.0kJ/mole IC50: 6.20E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29029BDBM29029(cyanohydroxybutenamide, 19)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.2kJ/mole IC50: 8.60E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29030BDBM29030(cyanohydroxybutenamide, 20)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.8kJ/mole IC50: 9.90E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29031BDBM29031(cyanohydroxybutenamide, 21)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.8kJ/mole IC50: 1.02E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29031BDBM29031(cyanohydroxybutenamide, 21)
Affinity DataKi:  2.00E+3nM IC50: 1.65E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29025BDBM29025(cyanohydroxybutenamide, 10)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.5kJ/mole IC50: 2.57E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29036BDBM29036(cyanohydroxybutenamide, 26)
Affinity DataKi:  3.20E+3nM ΔG°:  -31.4kJ/mole IC50: 2.72E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29037BDBM29037(cyanohydroxybutenamide, 27)
Affinity DataKi:  5.60E+3nM ΔG°:  -30.0kJ/mole IC50: 4.74E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29032BDBM29032(cyanohydroxybutenamide, 22)
Affinity DataKi:  5.80E+3nM ΔG°:  -29.9kJ/mole IC50: 4.91E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29038BDBM29038(cyanohydroxybutenamide, 28)
Affinity DataKi:  6.00E+3nM ΔG°:  -29.8kJ/mole IC50: 5.11E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29033BDBM29033(cyanohydroxybutenamide, 23)
Affinity DataKi:  6.80E+3nM ΔG°:  -29.5kJ/mole IC50: 5.72E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 29033BDBM29033(cyanohydroxybutenamide, 23)
Affinity DataKi:  1.07E+4nM IC50: 8.66E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29024BDBM29024(CHEMBL141732 | cyanocyclopropylpropenamide, 4)
Affinity DataKi:  1.10E+4nM ΔG°:  -28.3kJ/mole IC50: 9.25E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29034BDBM29034(cyanohydroxybutenamide, 24)
Affinity DataKi:  2.05E+4nM ΔG°:  -26.8kJ/mole IC50: 1.65E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29039BDBM29039(cyanohydroxybutenamide, 29)
Affinity DataKi:  2.15E+4nM ΔG°:  -26.6kJ/mole IC50: 1.82E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 14712BDBM14712(A77 1726 | CHEMBL973 | (2Z)-2-cyano-3-hydroxy-N-[4...)
Affinity DataKi:  2.20E+4nM ΔG°:  -26.6kJ/mole IC50: 1.90E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29026BDBM29026(CHEMBL142996 | cyanocyclopropylpropenamide, 11)
Affinity DataKi:  2.60E+4nM ΔG°:  -26.2kJ/mole IC50: 2.24E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandChemical structure of BindingDB Monomer ID 29035BDBM29035(cyanohydroxybutenamide, 25)
Affinity DataKi:  2.80E+4nM ΔG°:  -26.0kJ/mole IC50: 2.37E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed